B8HFF3 (B8HFF3_ARTCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase HAMAP MF_00114
Short name=DERA HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase HAMAP MF_00114
Phosphodeoxyriboaldolase HAMAP MF_00114

Gene names

Name:	deoC HAMAP MF_00114
Ordered Locus Names:	Achl_1301

Organism

Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]

Taxonomic identifier

452863 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979
Subcellular location	Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS022979 HAMAP MF_00114
Ligand	Schiff base HAMAP MF_00114 SAAS SAAS022979
Molecular function	Lyase HAMAP MF_00114 SAAS SAAS022979 EMBL ACL39292.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	169	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	198	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	B8HFF3 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 49D71EF503867222	FASTA	238	23,852
	10 20 30 40 50 60 MSNEATPSVQ PAAAAARNIA SYIDHTLLKP EASEADVLKA CAEAAEYGFK SVCVNPVWVK 70 80 90 100 110 120 TVKKALKGSG VLTCSVVGFP LGATPTDVKT FEARGAVLDG ADEVDMVINI AAARADDKGA 130 140 150 160 170 180 LTEDIASVAE AVHASGAILK VIIETSLLSD SQKVLACEAA VAAGADFVKT STGFNGGGAT 190 200 210 220 230 AEDVALMRRT VGPELGVKAS GGVRSLADAQ AMIAAGATRI GASSGIAIVK GEQGSSAY

References

[1]

"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001341 Genomic DNA. Translation: ACL39292.1.
RefSeq	YP_002487381.1. NC_011886.1.
3D structure databases
ProteinModelPortal	B8HFF3.
ModBase	Search...
Protein-protein interaction databases
STRING	B8HFF3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7292748.
GenomeReviews	Gene locus Achl_1301 in contig CP001341_GR.
KEGG	ach:Achl_1301.
PATRIC	20989127. VBIArtChl38304_1960.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG636421.
OMA	IDHTNLK.
ProtClustDB	PRK00507.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8HFF3_ARTCA

Accession

Primary (citable) accession number: B8HFF3

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)