B8HCH1 (B8HCH1_ARTCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pantothenate kinase HAMAP MF_00215 RuleBase RU003530
EC=2.7.1.33 HAMAP MF_00215 RuleBase RU003530

Alternative name(s):
Pantothenic acid kinase HAMAP MF_00215

Gene names

Name:	coaA HAMAP MF_00215
Ordered Locus Names:	Achl_2622

Organism

Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]

Taxonomic identifier

452863 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Subcellular location	Cytoplasm By similarity HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566.
Sequence similarities	Belongs to the prokaryotic pantothenate kinase family. HAMAP MF_00215 RuleBase RU003530

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Cellular component	Cytoplasm HAMAP MF_00215 RuleBase RU003530 SAAS SAAS004566
Ligand	ATP-binding HAMAP MF_00215 RuleBase RU003528 SAAS SAAS004566 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00215 RuleBase RU003528 SAAS SAAS004566 EMBL ACL40587.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP pantothenate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	109 – 116	8	ATP By similarity HAMAP MF_00215

Sequences

	Sequence		Length	Mass (Da)
	B8HCH1 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: DE56B3EA7CF4FADD	FASTA	331	37,943
	10 20 30 40 50 60 MRGARGRISN VTLQRNEANG EGASPFVELD RQTWSRLAAQ MEQPLNEEDI VRLRGLGDPL 70 80 90 100 110 120 DMKEIREVYL PLSRLLHLYV EAAGQLHAAT TTFLGEQTQR TPFVIGVAGS VAVGKSTIAR 130 140 150 160 170 180 VLREMLRRWP GTPNVELITT DGFLYPLAEL KRRQLLDRKG FPESYDRRAL LRFVSEIKGG 190 200 210 220 230 240 AEEVHAPWYS HVTYDIVPEK EVVVRRPDVL IVEGLNVLAP ARPRHDGRQG LALSDFFDFS 250 260 270 280 290 300 IYVDAKTSYI EEWYVDRFRK LRTTAFAQPE SYFHRYASLS DDEAESTARD IWKRINEPNL 310 320 330 EENVLPTRGR AQLVLTKDSD HTIRRMLLRK V

References

[1]

"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001341 Genomic DNA. Translation: ACL40587.1.
RefSeq	YP_002488676.1. NC_011886.1.
3D structure databases
ProteinModelPortal	B8HCH1.
SMR	B8HCH1. Positions 23-331.
ModBase	Search...
Protein-protein interaction databases
STRING	B8HCH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7294098.
GenomeReviews	Gene locus Achl_2622 in contig CP001341_GR.
KEGG	ach:Achl_2622.
PATRIC	20991879. VBIArtChl38304_3307.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG732538.
OMA	EVYLPLS.
ProtClustDB	PRK05439.
Family and domain databases
HAMAP	MF_00215. Pantothen_kinase_1. [Tree]
InterPro	IPR004566. PanK_bact. IPR006083. PRK/URK. [Graphical view]
KO	K00867.
PANTHER	PTHR10285:SF7. PanK_bact. 1 hit.
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PIRSF	PIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMs	TIGR00554. PanK_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8HCH1_ARTCA

Accession

Primary (citable) accession number: B8HCH1

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)