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B8HCG9

- ACPS_ARTCA

UniProt

B8HCG9 - ACPS_ARTCA

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Protein
Holo-[acyl-carrier-protein] synthase
Gene
acpS, Achl_2620
Organism
Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity.UniRule annotation

Catalytic activityi

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi8 – 81Magnesium By similarity
Metal bindingi50 – 501Magnesium By similarity

GO - Molecular functioni

  1. holo-[acyl-carrier-protein] synthase activity Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-HAMAP
  2. macromolecule biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciACHL452863:GH1A-2673-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Holo-[acyl-carrier-protein] synthase (EC:2.7.8.7)
Short name:
Holo-ACP synthase
Alternative name(s):
4'-phosphopantetheinyl transferase AcpS
Gene namesi
Name:acpS
Ordered Locus Names:Achl_2620
OrganismiArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Taxonomic identifieri452863 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
ProteomesiUP000002505: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 115115Holo-[acyl-carrier-protein] synthaseUniRule annotation
PRO_1000118789Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi452863.Achl_2620.

Structurei

3D structure databases

ProteinModelPortaliB8HCG9.
SMRiB8HCG9. Positions 1-115.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG274589.
HOGENOMiHOG000014315.
KOiK00997.
OMAiSMSHDAG.
OrthoDBiEOG6W7266.

Family and domain databases

Gene3Di3.90.470.20. 1 hit.
HAMAPiMF_00101. AcpS.
InterProiIPR008278. 4-PPantetheinyl_Trfase_SF.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase_dom.
[Graphical view]
PfamiPF01648. ACPS. 1 hit.
[Graphical view]
ProDomiPD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF56214. SSF56214. 1 hit.
TIGRFAMsiTIGR00556. pantethn_trn. 1 hit.

Sequencei

Sequence statusi: Complete.

B8HCG9-1 [UniParc]FASTAAdd to Basket

« Hide

MIVGIGVDVV DIERFGRQLE RTPGLRDRLF VPAERELNTR SLAARFAAKE    50
AVAKVLGAPA GMNWQDCWIG LDHNGPTVQV KGTVLAVAEA KGVKRWHLSI 100
SHDGGIATAT VLAEG 115
Length:115
Mass (Da):12,326
Last modified:March 3, 2009 - v1
Checksum:iBBEA870E7884A822
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001341 Genomic DNA. Translation: ACL40585.1.
RefSeqiYP_002488674.1. NC_011886.1.

Genome annotation databases

EnsemblBacteriaiACL40585; ACL40585; Achl_2620.
GeneIDi7294096.
KEGGiach:Achl_2620.
PATRICi20991875. VBIArtChl38304_3305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001341 Genomic DNA. Translation: ACL40585.1 .
RefSeqi YP_002488674.1. NC_011886.1.

3D structure databases

ProteinModelPortali B8HCG9.
SMRi B8HCG9. Positions 1-115.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 452863.Achl_2620.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL40585 ; ACL40585 ; Achl_2620 .
GeneIDi 7294096.
KEGGi ach:Achl_2620.
PATRICi 20991875. VBIArtChl38304_3305.

Phylogenomic databases

eggNOGi NOG274589.
HOGENOMi HOG000014315.
KOi K00997.
OMAi SMSHDAG.
OrthoDBi EOG6W7266.

Enzyme and pathway databases

BioCyci ACHL452863:GH1A-2673-MONOMER.

Family and domain databases

Gene3Di 3.90.470.20. 1 hit.
HAMAPi MF_00101. AcpS.
InterProi IPR008278. 4-PPantetheinyl_Trfase_SF.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase_dom.
[Graphical view ]
Pfami PF01648. ACPS. 1 hit.
[Graphical view ]
ProDomi PD004282. PPantethiene-prot_Trfase. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF56214. SSF56214. 1 hit.
TIGRFAMsi TIGR00556. pantethn_trn. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Entry informationi

Entry nameiACPS_ARTCA
AccessioniPrimary (citable) accession number: B8HCG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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