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B8HCG9

- ACPS_ARTCA

UniProt

B8HCG9 - ACPS_ARTCA

Protein

Holo-[acyl-carrier-protein] synthase

Gene

acpS

Organism
Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.UniRule annotation

    Catalytic activityi

    CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi8 – 81MagnesiumUniRule annotation
    Metal bindingi50 – 501MagnesiumUniRule annotation

    GO - Molecular functioni

    1. holo-[acyl-carrier-protein] synthase activity Source: UniProtKB-HAMAP
    2. magnesium ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-HAMAP
    2. macromolecule biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    BioCyciACHL452863:GH1A-2673-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Holo-[acyl-carrier-protein] synthaseUniRule annotation (EC:2.7.8.7UniRule annotation)
    Short name:
    Holo-ACP synthaseUniRule annotation
    Alternative name(s):
    4'-phosphopantetheinyl transferase AcpSUniRule annotation
    Gene namesi
    Name:acpSUniRule annotation
    Ordered Locus Names:Achl_2620
    OrganismiArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
    Taxonomic identifieri452863 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
    ProteomesiUP000002505: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 115115Holo-[acyl-carrier-protein] synthasePRO_1000118789Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi452863.Achl_2620.

    Structurei

    3D structure databases

    ProteinModelPortaliB8HCG9.
    SMRiB8HCG9. Positions 1-115.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the P-Pant transferase superfamily. AcpS family.UniRule annotation

    Phylogenomic databases

    eggNOGiNOG274589.
    HOGENOMiHOG000014315.
    KOiK00997.
    OMAiSMSHDAG.
    OrthoDBiEOG6W7266.

    Family and domain databases

    Gene3Di3.90.470.20. 1 hit.
    HAMAPiMF_00101. AcpS.
    InterProiIPR008278. 4-PPantetheinyl_Trfase_SF.
    IPR002582. ACPS.
    IPR004568. PPantethiene-prot_Trfase_dom.
    [Graphical view]
    PfamiPF01648. ACPS. 1 hit.
    [Graphical view]
    ProDomiPD004282. PPantethiene-prot_Trfase. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF56214. SSF56214. 1 hit.
    TIGRFAMsiTIGR00556. pantethn_trn. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B8HCG9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIVGIGVDVV DIERFGRQLE RTPGLRDRLF VPAERELNTR SLAARFAAKE    50
    AVAKVLGAPA GMNWQDCWIG LDHNGPTVQV KGTVLAVAEA KGVKRWHLSI 100
    SHDGGIATAT VLAEG 115
    Length:115
    Mass (Da):12,326
    Last modified:March 3, 2009 - v1
    Checksum:iBBEA870E7884A822
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001341 Genomic DNA. Translation: ACL40585.1.
    RefSeqiYP_002488674.1. NC_011886.1.

    Genome annotation databases

    EnsemblBacteriaiACL40585; ACL40585; Achl_2620.
    GeneIDi7294096.
    KEGGiach:Achl_2620.
    PATRICi20991875. VBIArtChl38304_3305.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001341 Genomic DNA. Translation: ACL40585.1 .
    RefSeqi YP_002488674.1. NC_011886.1.

    3D structure databases

    ProteinModelPortali B8HCG9.
    SMRi B8HCG9. Positions 1-115.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 452863.Achl_2620.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL40585 ; ACL40585 ; Achl_2620 .
    GeneIDi 7294096.
    KEGGi ach:Achl_2620.
    PATRICi 20991875. VBIArtChl38304_3305.

    Phylogenomic databases

    eggNOGi NOG274589.
    HOGENOMi HOG000014315.
    KOi K00997.
    OMAi SMSHDAG.
    OrthoDBi EOG6W7266.

    Enzyme and pathway databases

    BioCyci ACHL452863:GH1A-2673-MONOMER.

    Family and domain databases

    Gene3Di 3.90.470.20. 1 hit.
    HAMAPi MF_00101. AcpS.
    InterProi IPR008278. 4-PPantetheinyl_Trfase_SF.
    IPR002582. ACPS.
    IPR004568. PPantethiene-prot_Trfase_dom.
    [Graphical view ]
    Pfami PF01648. ACPS. 1 hit.
    [Graphical view ]
    ProDomi PD004282. PPantethiene-prot_Trfase. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF56214. SSF56214. 1 hit.
    TIGRFAMsi TIGR00556. pantethn_trn. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

    Entry informationi

    Entry nameiACPS_ARTCA
    AccessioniPrimary (citable) accession number: B8HCG9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3