B8HB51 (B8HB51_ARTCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase 1 HAMAP MF_00259
EC=2.1.2.10 HAMAP MF_00259

Alternative name(s):
Glycine cleavage system T protein 1 HAMAP MF_00259

Gene names

Name:	gcvT1 HAMAP MF_00259
Ordered Locus Names:	Achl_0537

Organism

Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]

Taxonomic identifier

452863 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	382 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. HAMAP MF_00259 RuleBase RU003981 SAAS SAAS022903
Sequence similarities	Belongs to the GcvT family. HAMAP MF_00259 RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase HAMAP MF_00259 SAAS SAAS022903 RuleBase RU003981 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8HB51 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 780E2E22CA008B56	FASTA	382	39,835
	10 20 30 40 50 60 MTENYTALYE QHKKAGASFT DFGGWQMPLK YSSELAEHHA VRTAAGLFDL SHMGEVWVTG 70 80 90 100 110 120 PDAAAFLDYA LVGKLSAIAV GKAKYSLICD TDGGIIDDLI TYRLPAGADG TAKYLVVPNA 130 140 150 160 170 180 GNAKVVAEAL QERAAGFDVT VQDASAETSL IAVQGPAAEA ILLALVPAGQ HSLVTELKYY 190 200 210 220 230 240 AAVEVGITVN GAVQDLLVAR TGYTGEDGFE IYAGNLEAAA LWEALLAAGE GSGLIPAGLA 250 260 270 280 290 300 ARDSLRLEAG MPLYGNELSR RVNAYAAGLG PVVSLAKESD FVGKEALAAL KAAGVGSTVG 310 320 330 340 350 360 QKLVGLKGTG RRAARGHYPV LKDGSLIGEV TSGQPSPTLG YPVAMAYVDV EFAEAGTLVD 370 380 VDLRGKPERF EVVALPFYKR QK

References

[1]

"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001341 Genomic DNA. Translation: ACL38536.1.
RefSeq	YP_002486625.1. NC_011886.1.
3D structure databases
ProteinModelPortal	B8HB51.
ModBase	Search...
Protein-protein interaction databases
STRING	B8HB51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7291964.
GenomeReviews	Gene locus Achl_0537 in contig CP001341_GR.
KEGG	ach:Achl_0537.
PATRIC	20987555. VBIArtChl38304_1193.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299834.
OMA	KALYGGM.
ProtClustDB	PRK00389.
Family and domain databases
HAMAP	MF_00259. GcvT. [Tree]
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR022903. NH2_Me_Trfase. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8HB51_ARTCA

Accession

Primary (citable) accession number: B8HB51

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)