B8HB30 (B8HB30_ARTCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-oxoglutarate dehydrogenase, E1 subunit EMBL ACL40344.1

Gene names

Ordered Locus Names:

Achl_2379

Organism

Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]

Taxonomic identifier

452863 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	1266 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423

Ontologies

Keywords
Ligand	Thiamine pyrophosphate SAAS SAAS001017
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular function	oxoglutarate dehydrogenase (succinyl-transferring) activity Inferred from electronic annotation. Source: InterPro thiamine pyrophosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring acyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8HB30 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: E7F2FA8F9756FE16	FASTA	1,266	139,120
	10 20 30 40 50 60 MPEQPSHRLP EEFGGNEWLV DELYEQYQQD KNAVDAKWWP LFESFDSGSS SSSNGHSANA 70 80 90 100 110 120 AANPPTTKMP IVNAAPAAPA QSPAAAPPAP AAAPAAAPSA PAPAKKAPAT EARDGGRKPA 130 140 150 160 170 180 AGAQPIPAQL PKNVKAPTAP EEDVVSVLRG PAKAIATNMV TSLEVPTATS VRAIPAKLLI 190 200 210 220 230 240 DNRVVINSNL ARARGGKVSF THLIGYAVIR ALSQFPSMNV YYDEVDGKPV AVQPAHVNFG 250 260 270 280 290 300 IAIDMPKPDG TRLLMVPNIK KAETLNFAEF WHTYEDLIKR ARNGKLTADD HQGTTVSLTN 310 320 330 340 350 360 PGGIGTVHSV PRLSKGQAAI IGVGALDYPA EFQGASEKII AQNAISKVLT LTSTYDHRVI 370 380 390 400 410 420 QGAGSGEFLK LVHQLLLGAQ NFYDEIFEAL RIPYEPVRWS PDLQVDPADE INKVARIQQL 430 440 450 460 470 480 IHSFRVRGHL MADTDPLEYV QRKHPDLDVL TYGLTLWDLD REWPTGGFGG KPMLKFRDIL 490 500 510 520 530 540 GVLRDAYCRT TGIEYMHIQE PEERKWFQDQ LEHPYSKPSR EEQLRIVSRL NAAEAFETFL 550 560 570 580 590 600 QTKFVGQKRF SLEGGESLIP LLDAVISEAA DDGLDEVAIG MAHRGRLNVL TNIAGKTYAQ 610 620 630 640 650 660 VFREFEGTQD PRSVQGSGDV KYHLGTEGTF TSENGNETKV YLAANPSHLE AVDSVLEGIV 670 680 690 700 710 720 RAKQDRLDQG EAFPVLPIMV HGDAAFAGQG VVAETLNLSQ LRGYRTGGTI HVVVNNQVGF 730 740 750 760 770 780 TTAPSSSRSS TYSTDVAKMI QAPVFHVNGD DPEAVVRIGQ LAYEFRQRFH KDVVIDMVCY 790 800 810 820 830 840 RRRGHNEGDD PSMTQPMMYN LIEAKRSVRK LYTEALIGRG DITEEEAEQL LRDYQERLER 850 860 870 880 890 900 VFAETHAAQT SPIPIVTADS AAVSDIERPI AQQSDFGTNA PANTAISADT LARIGKAHVE 910 920 930 940 950 960 IPDGFTVHAK LKQLLEKREQ MSREGGIDWG FGEIAAFGSL IMEGVPVRLA GQDSRRGTFV 970 980 990 1000 1010 1020 QRHAVFHDRA NGNEWLPLGN LSDDQAKLWI YDSLLSEYAA MGFEYGYSVE RPDALVLWEA 1030 1040 1050 1060 1070 1080 QFGDFVNGAQ TIIDEFISSA EQKWGQRSSL VLMLPHGYEG QGPDHSSARI ERFLQMCAEQ 1090 1100 1110 1120 1130 1140 NMIVANPTTA ASHFHLLRRQ AYSRPRKPLI IFTPKQLLRL KAAASSVEDF TTGTFRPVIA 1150 1160 1170 1180 1190 1200 EHEHLDANAV ERVLLVSGRL YYDLLSTRQK TGDKTTAIVR VEQLYPLPSD DIAAELAKYP 1210 1220 1230 1240 1250 1260 NAEVVWAQDE PANQGPWPFI GLNLPDALDR RVRLVSRPAS ASTAAGSMKR HAAEQDVLLK QAFARK

References

[1]

"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001341 Genomic DNA. Translation: ACL40344.1.
RefSeq	YP_002488433.1. NC_011886.1.
3D structure databases
ProteinModelPortal	B8HB30.
ModBase	Search...
Protein-protein interaction databases
STRING	B8HB30.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7293852.
GenomeReviews	Gene locus Achl_2379 in contig CP001341_GR.
KEGG	ach:Achl_2379.
PATRIC	20991387. VBIArtChl38304_3064.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289950.
OMA	EGDEPAF.
ProtClustDB	PRK12270.
Family and domain databases
InterPro	IPR001078. 2-oxoacid_DH_actylTfrase. IPR011603. 2oxoglutarate_DH_E1. IPR023213. CAT-like_dom. IPR001017. DH_E1. IPR005475. Transketolase-like_Pyr-bd. [Graphical view]
Gene3D	G3DSA:3.30.559.10. CAT-like_dom. 1 hit.
KO	K00164.
PANTHER	PTHR23152. 2oxoglutarate_DH_E1. 1 hit.
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00676. E1_dh. 1 hit. PF02779. Transket_pyr. 1 hit. [Graphical view]
PIRSF	PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
TIGRFAMs	TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8HB30_ARTCA

Accession

Primary (citable) accession number: B8HB30

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)