B8HAT7 (MQO_ARTCA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	Achl_2286

Organism

Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]

Taxonomic identifier

452863 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 500	500	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000124761

Sequences

	Sequence		Length	Mass (Da)
	B8HAT7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 65644B951E2AACD9	FASTA	500	54,076
	10 20 30 40 50 60 MTFISKTQHA DVVLIGGGIM SATLGAFLKQ LEPNWTISLF ERLDQPGLES SDPWNNAGTG 70 80 90 100 110 120 HAALCELNYS PAAKDGSVSP AKALLINEQF QLSRQFWSHL VDGNLIGSPK GFINTVPHMS 130 140 150 160 170 180 FVIGDDHTRF LKTRYEALKP HTLFRSMEYS EDHGQIAKWA PLIVKGRNAQ QKVAATRAAE 190 200 210 220 230 240 GTDVDFGALT RELTTYLGNN GVEINYGHDV TGISKASDGG WDLTLKHPRS GEHGRIHAKF 250 260 270 280 290 300 VFVGAGGGAL HLLQASGIPE SKGYGGFPVS GQFFRCTDET IAAQHSAKVY GQASVGAPPM 310 320 330 340 350 360 SVPHLDTRYV NGKRSLLFGP YAGFSTNFLK NGSYLDLPLS IRPGNIIPML AVAKDNMDLT 370 380 390 400 410 420 AYLIKEVAKR HGDKVEALRE YYPEAKDGDW ELITAGQRVQ IIKKDPQKGG ILQFGTEVIA 430 440 450 460 470 480 GRDGSIGALL GASPGASTAV PIMIELLQKT FPKNFKGWQG KLKDMMPGYG VKLDENPELA 490 500 AELERATAKS LQLESVSASN

References

[1]

"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001341 Genomic DNA. Translation: ACL40251.1.
RefSeq	YP_002488340.1. NC_011886.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8HAT7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7293758.
GenomeReviews	Gene locus Achl_2286 in contig CP001341_GR.
KEGG	ach:Achl_2286.
PATRIC	20991199. VBIArtChl38304_2971.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	REMIPSY.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_ARTCA

Accession

Primary (citable) accession number: B8HAT7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program