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B8H9P1 (B8H9P1_ARTCA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:Achl_2142
OrganismArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]
Taxonomic identifier452863 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length383 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity SAAS SAAS011529 HAMAP MF_00456.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain291 – 36979PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
B8H9P1 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 7A07E64294852872

FASTA38339,442
        10         20         30         40         50         60 
MSPRATATEP ASGSVDRSAL AGARRVVVKV GSSSLTSIKG GISEESLTAL ADALAAKRNS 

        70         80         90        100        110        120 
GTEIILVSSG AIAAGLAPLG LAKRPRDLAT QQAAASVGQG LLMARYTQAF GAHGVTVSQV 

       130        140        150        160        170        180 
LLTAEDLMRR SQHTNALRAM DRLLNLGVVP VVNENDTVAT HEIRFGDNDR LAALVAHLVR 

       190        200        210        220        230        240 
ADALVLLSDV DSLYDGPPAQ GAKRIPLVTG AHDLEGVSIG KTGKAGVGTG GMLTKVEAAS 

       250        260        270        280        290        300 
MAAGSGIHAL VTSTPNAAAA LNGEDVGTWF TVNGARKPVR LLWLAHVASV QGRLILDEGA 

       310        320        330        340        350        360 
VRAVRHHRTS LLPAGISAVH GVFEAGDAVE IAGADGTIVA RGLVNYSSEE LPRMLGRSTR 

       370        380 
DLGEELGTGY DREVVHVDDL VLV

« Hide

References

[1]"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001341 Genomic DNA. Translation: ACL40110.1.
RefSeqYP_002488199.1. NC_011886.1.

3D structure databases

ProteinModelPortalB8H9P1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8H9P1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7293605.
GenomeReviewsGene locus Achl_2142 in contig CP001341_GR.
KEGGach:Achl_2142.
PATRIC20990877. VBIArtChl38304_2819.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG507643.
OMATFGDNDM.
ProtClustDBPRK05429.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8H9P1_ARTCA
AccessionPrimary (citable) accession number: B8H9P1
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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