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B8H8N2 (B8H8N2_ARTCA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163
Gene names
Name:def2 HAMAP MF_00163
Ordered Locus Names:Achl_1935
OrganismArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]
Taxonomic identifier452863 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length226 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1741 By similarity HAMAP MF_00163
Metal binding1311Iron By similarity HAMAP MF_00163
Metal binding1731Iron By similarity HAMAP MF_00163
Metal binding1771Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
B8H8N2 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 7777706D21EAA4F3

FASTA22624,311
        10         20         30         40         50         60 
MTFPAPSTDL TAEQIRETVD RILSAGTLPP IVQAGHPALR QKAAPFDGQI TPEQLARLIE 

        70         80         90        100        110        120 
LMRQVMHEAP GVGLAAPQLG IPLQLAVLED KYDVDHEAAA LRNRAPLDFL AILNPSYTPA 

       130        140        150        160        170        180 
GPDRAAFYEG CLSLNGLQAV VSRPQAVLLD FVRPDGGAER RGFSGWQARI VQHETDHLNG 

       190        200        210        220 
ILYVDRAQLR SLSSNAEYAA HWAEPGIGKA REGLGFDDGP AGISVP

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References

[1]"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001341 Genomic DNA. Translation: ACL39910.1.
RefSeqYP_002487999.1. NC_011886.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB8H8N2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7293396.
GenomeReviewsGene locus Achl_1935 in contig CP001341_GR.
KEGGach:Achl_1935.
PATRIC20990449. VBIArtChl38304_2607.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG665227.
OMAGWQARIV.
ProtClustDBPRK00150.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8H8N2_ARTCA
AccessionPrimary (citable) accession number: B8H8N2
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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