Skip Header

Contribute Send feedback
Read comments (?) or add your own

B8H7T9 (MTLD_ARTCA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mannitol-1-phosphate 5-dehydrogenase
EC=1.1.1.17
Gene names
Name:mtlD
Ordered Locus Names:Achl_3788
OrganismArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]
Taxonomic identifier452863 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196

Sequence similarities

Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncoenzyme binding

Inferred from electronic annotation. Source: InterPro

mannitol-1-phosphate 5-dehydrogenase activity

Inferred from electronic annotation. Source: EC

nucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 387387Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196
PRO_1000124383

Regions

Nucleotide binding3 – 1412NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
B8H7T9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 0B57EEC1CC7684C7

FASTA38740,718
        10         20         30         40         50         60 
MKAVHFGAGN IGRGFVGLLL HNAGYEVVFA DVAEGLIAQL ADADSYAVHE VGESPAVQTV 

        70         80         90        100        110        120 
DNFRALNSNT QEAELITEIA TADIVTTAVG PHILKFVAPV IARGIAARGA GMAPLQVMAC 

       130        140        150        160        170        180 
ENAINATDVL AREVASRPEA AGGALDGQAV FANTAVDRIV PNQEAGQGLD VTVESFYEWV 

       190        200        210        220        230        240 
IDRTAFAGSE PEIPGATFVD ELAPYIERKL FTVNTGHASA AYFGFEAGLE KISDAMADQD 

       250        260        270        280        290        300 
VAEDVRAVLE ETKQLLVAKH GFSNEAQEAY VQKILVRFTN PHLPDTVNRV GRAPLRKLSR 

       310        320        330        340        350        360 
HERFIGPAAE LAERGVVPEA LLGAISAALR FTDPADAEAT ELAGILASGS AADATARITG 

       370        380 
LDPDHPLFNA VSTLVEERQA ELAATSA

« Hide

References

[1]"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001341 Genomic DNA. Translation: ACL41742.1.
RefSeqYP_002489831.1. NC_011886.1.

3D structure databases

ProteinModelPortalB8H7T9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8H7T9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7295276.
GenomeReviewsGene locus Achl_3788 in contig CP001341_GR.
KEGGach:Achl_3788.
PATRIC20994231. VBIArtChl38304_4471.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG568825.
OMAFANTAVD.
ProtClustDBPRK02318.

Family and domain databases

HAMAPMF_00196. Mannitol_dehydrog.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR023028. Mannitol_1_phos_5_DH.
IPR000669. Mannitol_DH.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00009.
PfamPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
PRINTSPR00084. MTLDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
PROSITEPS00974. MANNITOL_DHGENASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMTLD_ARTCA
AccessionPrimary (citable) accession number: B8H7T9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents