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B8H7M5

- PGK_ARTCA

UniProt

B8H7M5 - PGK_ARTCA

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Protein

Phosphoglycerate kinase

Gene
pgk, Achl_1829
Organism
Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391Substrate By similarity
Binding sitei121 – 1211Substrate By similarity
Binding sitei161 – 1611Substrate By similarity
Binding sitei211 – 2111ATP By similarity
Binding sitei307 – 3071ATP; via carbonyl oxygen By similarity
Binding sitei338 – 3381ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi364 – 3674ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciACHL452863:GH1A-1866-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Achl_1829
OrganismiArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Taxonomic identifieri452863 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
ProteomesiUP000002505: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Phosphoglycerate kinaseUniRule annotationPRO_1000192793Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi452863.Achl_1829.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate binding By similarity
Regioni62 – 654Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

B8H7M5-1 [UniParc]FASTAAdd to Basket

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MTSHTLNELI AEGVRGRYIL VRSDLNVPLD GSTVTDDGRI KASLPVLAKL    50
TDAGARVLVT AHLGRPKGAP EDKYSLRPAV DRLAELAGFK VTLAADTVGD 100
SAREAAASLQ DGEALVLENV RFDARETSKD DAERGAFADE LVALTGANGA 150
YVDDAFGAVH RKHASVYDVA SRLPSYQGDL VHTEVEVLRK LTADTQRPYV 200
VVLGGSKVSD KLAVIDNLIG KADTILVGGG MLFTFLAAAG HKVAASLLEQ 250
DQIGVVQDYL KRAADAGTEF VIPTDVVVAE KFAADAAHET VAADAIEASS 300
FGANGIGLDI GPDSAAAFAD RIKGARTVFW NGPMGVFEFE AFSAGTRAIA 350
QALTETEAFT VVGGGDSAAA VRTLGFADDQ FGHISTGGGA SLEYLEGKEL 400
PGLSILDR 408
Length:408
Mass (Da):42,558
Last modified:March 3, 2009 - v1
Checksum:iA26DEC49DE00DC83
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001341 Genomic DNA. Translation: ACL39805.1.
RefSeqiWP_015937025.1. NC_011886.1.
YP_002487894.1. NC_011886.1.

Genome annotation databases

EnsemblBacteriaiACL39805; ACL39805; Achl_1829.
GeneIDi7293289.
KEGGiach:Achl_1829.
PATRICi20990239. VBIArtChl38304_2503.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001341 Genomic DNA. Translation: ACL39805.1 .
RefSeqi WP_015937025.1. NC_011886.1.
YP_002487894.1. NC_011886.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 452863.Achl_1829.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL39805 ; ACL39805 ; Achl_1829 .
GeneIDi 7293289.
KEGGi ach:Achl_1829.
PATRICi 20990239. VBIArtChl38304_2503.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci ACHL452863:GH1A-1866-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Entry informationi

Entry nameiPGK_ARTCA
AccessioniPrimary (citable) accession number: B8H7M5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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