Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B8H632 (B8H632_CAUCN) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Histidine--tRNA ligase HAMAP-Rule MF_00127

EC=6.1.1.21 HAMAP-Rule MF_00127
Alternative name(s):
Histidyl-tRNA synthetase HAMAP-Rule MF_00127
Gene names
Name:hisS HAMAP-Rule MF_00127
Ordered Locus Names:CCNA_03628 EMBL ACL97093.1
OrganismCaulobacter crescentus (strain NA1000 / CB15N) [Complete proteome] [HAMAP] EMBL ACL97093.1
Taxonomic identifier565050 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter

Protein attributes

Sequence length495 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). HAMAP-Rule MF_00127

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00127

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00127 SAAS SAAS015807.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00127 RuleBase RU003746

Sequences

Sequence LengthMass (Da)Tools
B8H632 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 2AD14DC9B10A418E

FASTA49552,521
        10         20         30         40         50         60 
MTTDSEQPNT DFRPEARAPR GFADKRARDL RAERAILEAV SAVYERYGFE ALDTGAFEYA 

        70         80         90        100        110        120 
DALGKFLPDS DRPNEGVFAL QDDDDQWMAL RYDLTAPLAR FAAQNWETLP KPFRRYAFGP 

       130        140        150        160        170        180 
VWRNEKPGPG RFRQFIQCDA DTVGSARPEA DAEIIAMAVE GLEAAGLPRG TAVLKINNRK 

       190        200        210        220        230        240 
LLNGLLTAAG ADSAGQKLAV LRAVDKLDRL GVDGVRLLLG EGRLDESGDF TKGAGLKGKA 

       250        260        270        280        290        300 
VDQVLDFVQA GSTGGRAATL DNIARVVAGS AEGDEGLLEL SRIDAALSSL GIADDQAFID 

       310        320        330        340        350        360 
PSIVRGLEYY TGAVFEAELL LSTTDEKGNK VSFGSIGGGG RYDDLVARFT GNVTPATGFS 

       370        380        390        400        410        420 
FGVSRLAAAL RAAGREPGGA ARGPVVVITF DQAHMGEYFS VVGQLRAAGI AAEVYLGTSG 

       430        440        450        460        470        480 
MKPQMKYADR RGAPAVVMLG GDEIAAGTVT IKDLDAGRMA AEGLTDNAAW KAERPGQQTI 

       490 
PRDQLVDAVR KIIGG 

« Hide

References

[1]"The genetic basis of laboratory adaptation in Caulobacter crescentus."
Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V., Walunas T.L., Crosson S.
J. Bacteriol. 192:3678-3688(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NA1000 / CB15N.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001340 Genomic DNA. Translation: ACL97093.1.
RefSeqYP_002519001.1. NC_011916.1.

3D structure databases

ProteinModelPortalB8H632.
SMRB8H632. Positions 19-457.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING190650.CC_3513.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL97093; ACL97093; CCNA_03628.
GeneID7329712.
KEGGccs:CCNA_03628.
PATRIC21311743. VBICauCre52860_3541.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0124.
HOGENOMHOG000018071.
KOK01892.
OMAIFSITKA.
OrthoDBEOG6BPDH4.

Enzyme and pathway databases

BioCycCAULONA1000:CCNA_03628-MONOMER.

Family and domain databases

Gene3D3.40.50.800. 1 hit.
HAMAPMF_00127. His_tRNA_synth.
InterProIPR006195. aa-tRNA-synth_II.
IPR004154. Anticodon-bd.
IPR015807. His-tRNA-ligase.
IPR004516. HisRS/HisZ.
[Graphical view]
PANTHERPTHR11476. PTHR11476. 1 hit.
PfamPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
PIRSFPIRSF001549. His-tRNA_synth. 1 hit.
SUPFAMSSF52954. SSF52954. 1 hit.
TIGRFAMsTIGR00442. hisS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8H632_CAUCN
AccessionPrimary (citable) accession number: B8H632
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)