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B8H632

- B8H632_CAUCN

UniProt

B8H632 - B8H632_CAUCN

Protein

Histidine--tRNA ligase

Gene

hisS

Organism
Caulobacter crescentus (strain NA1000 / CB15N)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. histidine-tRNA ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. histidyl-tRNA aminoacylation Source: InterPro

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotationImported, Ligase

    Keywords - Biological processi

    Protein biosynthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCAULONA1000:CCNA_03628-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histidine--tRNA ligaseUniRule annotation (EC:6.1.1.21UniRule annotation)
    Alternative name(s):
    Histidyl-tRNA synthetaseUniRule annotation
    Gene namesi
    Name:hisSUniRule annotation
    Ordered Locus Names:CCNA_03628Imported
    OrganismiCaulobacter crescentus (strain NA1000 / CB15N)Imported
    Taxonomic identifieri565050 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaCaulobacteralesCaulobacteraceaeCaulobacter
    ProteomesiUP000001364: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi190650.CC_3513.

    Structurei

    3D structure databases

    ProteinModelPortaliB8H632.
    SMRiB8H632. Positions 19-457.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0124.
    HOGENOMiHOG000018071.
    KOiK01892.
    OMAiIFSITKA.
    OrthoDBiEOG6BPDH4.

    Family and domain databases

    Gene3Di3.40.50.800. 1 hit.
    HAMAPiMF_00127. His_tRNA_synth.
    InterProiIPR006195. aa-tRNA-synth_II.
    IPR004154. Anticodon-bd.
    IPR015807. His-tRNA-ligase.
    IPR004516. HisRS/HisZ.
    [Graphical view]
    PANTHERiPTHR11476. PTHR11476. 1 hit.
    PfamiPF03129. HGTP_anticodon. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001549. His-tRNA_synth. 1 hit.
    SUPFAMiSSF52954. SSF52954. 1 hit.
    TIGRFAMsiTIGR00442. hisS. 1 hit.
    PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8H632-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTDSEQPNT DFRPEARAPR GFADKRARDL RAERAILEAV SAVYERYGFE    50
    ALDTGAFEYA DALGKFLPDS DRPNEGVFAL QDDDDQWMAL RYDLTAPLAR 100
    FAAQNWETLP KPFRRYAFGP VWRNEKPGPG RFRQFIQCDA DTVGSARPEA 150
    DAEIIAMAVE GLEAAGLPRG TAVLKINNRK LLNGLLTAAG ADSAGQKLAV 200
    LRAVDKLDRL GVDGVRLLLG EGRLDESGDF TKGAGLKGKA VDQVLDFVQA 250
    GSTGGRAATL DNIARVVAGS AEGDEGLLEL SRIDAALSSL GIADDQAFID 300
    PSIVRGLEYY TGAVFEAELL LSTTDEKGNK VSFGSIGGGG RYDDLVARFT 350
    GNVTPATGFS FGVSRLAAAL RAAGREPGGA ARGPVVVITF DQAHMGEYFS 400
    VVGQLRAAGI AAEVYLGTSG MKPQMKYADR RGAPAVVMLG GDEIAAGTVT 450
    IKDLDAGRMA AEGLTDNAAW KAERPGQQTI PRDQLVDAVR KIIGG 495
    Length:495
    Mass (Da):52,521
    Last modified:March 3, 2009 - v1
    Checksum:i2AD14DC9B10A418E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001340 Genomic DNA. Translation: ACL97093.1.
    RefSeqiWP_010921342.1. NC_011916.1.
    YP_002519001.1. NC_011916.1.

    Genome annotation databases

    EnsemblBacteriaiACL97093; ACL97093; CCNA_03628.
    GeneIDi7329712.
    KEGGiccs:CCNA_03628.
    PATRICi21311743. VBICauCre52860_3541.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001340 Genomic DNA. Translation: ACL97093.1 .
    RefSeqi WP_010921342.1. NC_011916.1.
    YP_002519001.1. NC_011916.1.

    3D structure databases

    ProteinModelPortali B8H632.
    SMRi B8H632. Positions 19-457.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 190650.CC_3513.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL97093 ; ACL97093 ; CCNA_03628 .
    GeneIDi 7329712.
    KEGGi ccs:CCNA_03628.
    PATRICi 21311743. VBICauCre52860_3541.

    Phylogenomic databases

    eggNOGi COG0124.
    HOGENOMi HOG000018071.
    KOi K01892.
    OMAi IFSITKA.
    OrthoDBi EOG6BPDH4.

    Enzyme and pathway databases

    BioCyci CAULONA1000:CCNA_03628-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.800. 1 hit.
    HAMAPi MF_00127. His_tRNA_synth.
    InterProi IPR006195. aa-tRNA-synth_II.
    IPR004154. Anticodon-bd.
    IPR015807. His-tRNA-ligase.
    IPR004516. HisRS/HisZ.
    [Graphical view ]
    PANTHERi PTHR11476. PTHR11476. 1 hit.
    Pfami PF03129. HGTP_anticodon. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001549. His-tRNA_synth. 1 hit.
    SUPFAMi SSF52954. SSF52954. 1 hit.
    TIGRFAMsi TIGR00442. hisS. 1 hit.
    PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genetic basis of laboratory adaptation in Caulobacter crescentus."
      Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V., Walunas T.L., Crosson S.
      J. Bacteriol. 192:3678-3688(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NA1000 / CB15NImported.

    Entry informationi

    Entry nameiB8H632_CAUCN
    AccessioniPrimary (citable) accession number: B8H632
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3