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B8GVH4 (B8GVH4_CAUCN) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase 2 HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase 2 HAMAP MF_01174
Gene names
Name:astD2 HAMAP MF_01174
Ordered Locus Names:CCNA_01679
OrganismCaulobacter crescentus (strain NA1000 / CB15N) [Complete proteome] [HAMAP] EMBL ACL95144.1
Taxonomic identifier565050 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Caulobacterales › Caulobacteraceae › Caulobacter

Protein attributes

Sequence length485 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174 SAAS SAAS017649

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174 SAAS SAAS017649

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174 SAAS SAAS017649

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding221 – 2266NAD By similarity HAMAP MF_01174

Sites

Active site2441 By similarity HAMAP MF_01174
Active site2791 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
B8GVH4 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: BFD41A4A04E231B0

FASTA48550,840
        10         20         30         40         50         60 
MSGGLFIDGK WRAGQGAGLS STDPATGEDV WSAATATPAD VADAVAAARK AFPAWADRPR 

        70         80         90        100        110        120 
EERIAILRRY KDILVERAAP YAEALSRETG KALWETRAEL ASMAGKVDLS IRAYDERTGV 

       130        140        150        160        170        180 
TENAMPFGRA VLRHRAHGVM AVLGPFNFPG HLPNGHIVPA LLAGDTVVFK PSEETPLAGQ 

       190        200        210        220        230        240 
LMVEALEAAG APAGVVNLVQ GGRETGQALI AQDIDGLLFT GSAAAGTYFR RYFADRPDVI 

       250        260        270        280        290        300 
LALELGGNNP LVVWNADDAP EAVAALIVQS AFITTGQRCS CARRLIVPDD ASGAAIIEAT 

       310        320        330        340        350        360 
VALAERLVIG AWNAENEPFM GPLISGRAAK AAREVASATP GKTILALDGV AGLGDAFLKP 

       370        380        390        400        410        420 
GIVDVTGLET PDEELFAPLL QVRRVSSFDE ALAAANATRY GLSAGLISNE SELWDKFLSR 

       430        440        450        460        470        480 
IRAGVVNWNR PTTGAAGSMP FGGLGASGNH RPSAYYAADY CAYPVASFEA SMVVDTLKDI 


KGLKA

« Hide

References

[1]"The genetic basis of laboratory adaptation in Caulobacter crescentus."
Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V., Walunas T.L., Crosson S.
J. Bacteriol. 192:3678-3688(2010) [PubMed: 20472802] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NA1000.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001340 Genomic DNA. Translation: ACL95144.1.
RefSeqYP_002517052.1. NC_011916.1.

3D structure databases

ProteinModelPortalB8GVH4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8GVH4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7331739.
GenomeReviewsGene locus CCNA_01679 in contig CP001340_GR.
KEGGccs:CCNA_01679.
PATRIC21307919. VBICauCre52860_1653.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATHYIAGN.
PhylomeDBB8GVH4.
ProtClustDBCLSK890509.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8GVH4_CAUCN
AccessionPrimary (citable) accession number: B8GVH4
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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