B8GVB4 (B8GVB4_THISH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
NAD(+) synthase EMBL ACL73460.1
EC=6.3.1.5 EMBL ACL73460.1

Gene names

Ordered Locus Names:

Tgr7_2382

Organism

Thioalkalivibrio sp. (strain HL-EbGR7) [Complete proteome] [HAMAP]

Taxonomic identifier

396588 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Thioalkalivibrio

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. SAAS SAAS003694
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. SAAS SAAS003694

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS003694 NAD SAAS SAAS003694 Nucleotide-binding
Molecular function	Ligase SAAS SAAS003694 EMBL ACL73460.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro NAD+ synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8GVB4 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 25A0266ED11EDB72	FASTA	334	37,193
	10 20 30 40 50 60 MSQKLSPDVL KIDAEAEVER ISAALREILR KDLNRRGLII AISGGVDSAV CAALCVKALG 70 80 90 100 110 120 PGKVFGLLLP ERDSSSNSVR LGRMVAEQLG IEYTVEDIAP TLEAIGCYRW RDDAIRSVFP 130 140 150 160 170 180 DYDGTWKNKL VIQGGQQGQI NRFALVVQKP NGELAEERLD LKSYLQIVAA TNFKQRIRKT 190 200 210 220 230 240 LEYFHADRLN YAVVGTPNRL EYDQGFFVKN GDGSADVKPI AHLYKTQVYQ LARHLGLPEE 250 260 270 280 290 300 ICTAKPTTDT YSLPQGQDEF YFALPYDKMD LALWSLNHQV PAEELAAVLG CETRQAEWIY 310 320 330 RDIEAKRRTT RYLHARPAMV GSPTAASGVG TGMD

References

[1]

"Complete genome sequence of 'Thioalkalivibrio sulfidophilus' HL-EbGr7." Muyzer G., Sorokin D.Y., Mavromatis K., Lapidus A., Clum A., Ivanova N., Pati A., d'Haeseleer P., Woyke T., Kyrpides N.C. Stand. Genomic Sci. 4:23-35(2011) [PubMed: 21475584] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HL-EbGR7 EMBL ACL73460.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001339 Genomic DNA. Translation: ACL73460.1.
RefSeq	YP_002514447.1. NC_011901.1.
3D structure databases
ProteinModelPortal	B8GVB4.
ModBase	Search...
Protein-protein interaction databases
STRING	B8GVB4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7318171.
GenomeReviews	Gene locus Tgr7_2382 in contig CP001339_GR.
KEGG	tgr:Tgr7_2382.
PATRIC	23964292. VBIThiSp19295_2373.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG351567.
OMA	AHLYKSQ.
ProtClustDB	PRK00876.
Family and domain databases
HAMAP	MF_00193. NadE. [Tree]
InterPro	IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR022926. NH(3)-dep_NAD(+)_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K01916.
Pfam	PF02540. NAD_synthase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00552. NadE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8GVB4_THISH

Accession

Primary (citable) accession number: B8GVB4

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)