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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Thioalkalivibrio sulfidiphilus (strain HL-EbGR7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTSUL396588:G1GUK-262-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Tgr7_0263
OrganismiThioalkalivibrio sulfidiphilus (strain HL-EbGR7)
Taxonomic identifieri396588 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeThioalkalivibrio
Proteomesi
  • UP000002383 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001989401 – 586Arginine--tRNA ligaseAdd BLAST586

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi396588.Tgr7_0263

Structurei

3D structure databases

ProteinModelPortaliB8GU79
SMRiB8GU79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi128 – 138"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B8GU79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDQLQALIE QAIDALRQDG TLPGDTAVDV QVTRTKDKAH GDFATNVALQ
60 70 80 90 100
LAKPARKKPR DVAEAIVARL PASGLVARTE IAGPGFINLF LGEQAKLSVI
110 120 130 140 150
ATIREQGERY GRSQLGAGKK VQVEFVSANP TGPLHVGHGR GAAYGAAVAD
160 170 180 190 200
LLEAVGFDVH REYYVNDAGR QMDILGTSVW LRYLELTGVE LPFPTNAYRG
210 220 230 240 250
DYVYDIAATL HREHGDHYKR EAAEILDGLP PDEPDGGDKE EYIDAMIARA
260 270 280 290 300
KELLGDNHYR FVFELGLNVI LDDIRDDLAE FGVTYDTWYS ERSLTDKGAV
310 320 330 340 350
NLAIERLREA GHLYEKDGAL WFRSTDFGDE KDRVVQRDNG QTTYFASDIA
360 370 380 390 400
YHMDKMERGY DRVIDVWGAD HHGYVPRVKA ALKALGEDET RLDVLLVQFA
410 420 430 440 450
ILYRGGERVQ MSTRSGSFVT LRELREEVGK DAARFFYVMR RCEQHLDFDL
460 470 480 490 500
DLAKSQSADN PVYYIQYAHA RVCSVLRQME AKGLKHDPSH GEAKLSLLTE
510 520 530 540 550
SHEQEILATL ARFPEVIEAA ALVEEPHQIA NYLRELANDF HTYYNAHQFL
560 570 580
VDEPAIRDAR LSLILAVRQV IANGLGLLGV SAPQEM
Length:586
Mass (Da):65,513
Last modified:March 3, 2009 - v1
Checksum:iC1DA50E0DB9D5609
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001339 Genomic DNA Translation: ACL71362.1
RefSeqiWP_012636851.1, NC_011901.1

Genome annotation databases

EnsemblBacteriaiACL71362; ACL71362; Tgr7_0263
KEGGitgr:Tgr7_0263

Similar proteinsi

Entry informationi

Entry nameiSYR_THISH
AccessioniPrimary (citable) accession number: B8GU79
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: February 28, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome