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B8GP44

- PGK_THISH

UniProt

B8GP44 - PGK_THISH

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Protein

Phosphoglycerate kinase

Gene
pgk, Tgr7_2891
Organism
Thioalkalivibrio sp. (strain HL-EbGR7)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361Substrate By similarity
Binding sitei113 – 1131Substrate By similarity
Binding sitei146 – 1461Substrate By similarity
Binding sitei197 – 1971ATP By similarity
Binding sitei319 – 3191ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi345 – 3484ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTSUL396588:GH5B-2937-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Tgr7_2891
OrganismiThioalkalivibrio sp. (strain HL-EbGR7)
Taxonomic identifieri396588 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeThioalkalivibrio
ProteomesiUP000002383: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 392392Phosphoglycerate kinaseUniRule annotationPRO_1000192859Add
BLAST

Proteomic databases

PRIDEiB8GP44.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi396588.Tgr7_2891.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni59 – 624Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8GP44-1 [UniParc]FASTAAdd to Basket

« Hide

MSVIKMTDLD LAGKRVLIRE DLNVPVKDGK VTSDARIRAS LPTIEHAMKA    50
GAKVMLMSHL GRPEEGVFSE EDSLKPVAEH LSGLLGKEVR LVRDYLDGVD 100
VADGEVVLLE NVRFNKGEKK NEEGLSRKYA ALCDVYVMDA FGTAHRAQAS 150
THGAGQYAPV ACAGPLLAAE LEALGKALDN PKRPLVAIVG GSKVSTKLTV 200
LESLSKVVDQ LIVGGGIANT FIAAQGHPVG KSLYEADLVD EAKRLMAAAK 250
AKGGDIPVPT DVVTGKEFSE STPASTKRVS EVAADDMIFD VGPDTAASYA 300
DMLRKAGTIV WNGPVGVFEF DQFAAGTKAL GEAIADSDGF SIAGGGDTLA 350
AIDKYGLASR ISYISTGGGA FLEFLEGKKL PAVAMLEERA KG 392
Length:392
Mass (Da):41,117
Last modified:March 3, 2009 - v1
Checksum:iF11FD9EA5DC94760
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001339 Genomic DNA. Translation: ACL73964.1.
RefSeqiYP_002514951.1. NC_011901.1.

Genome annotation databases

EnsemblBacteriaiACL73964; ACL73964; Tgr7_2891.
GeneIDi7316996.
KEGGitgr:Tgr7_2891.
PATRICi23965276. VBIThiSp19295_2858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001339 Genomic DNA. Translation: ACL73964.1 .
RefSeqi YP_002514951.1. NC_011901.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 396588.Tgr7_2891.

Proteomic databases

PRIDEi B8GP44.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL73964 ; ACL73964 ; Tgr7_2891 .
GeneIDi 7316996.
KEGGi tgr:Tgr7_2891.
PATRICi 23965276. VBIThiSp19295_2858.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci TSUL396588:GH5B-2937-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HL-EbGR7.

Entry informationi

Entry nameiPGK_THISH
AccessioniPrimary (citable) accession number: B8GP44
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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