B8GMA8 (DCD_THISH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Tgr7_2620

Organism

Thioalkalivibrio sp. (strain HL-EbGR7) [Complete proteome] [HAMAP]

Taxonomic identifier

396588 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Thioalkalivibrio › Thioalkalivibrio sulfidophilus

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000123160

Sequences

	Sequence		Length	Mass (Da)
	B8GMA8 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: DE0C786F5392143F	FASTA	188	21,098
	10 20 30 40 50 60 MSIKSDRWIR RMAEQHGMIE PFEPGQVRHA GEERIVSYGT SSYGYDVRCA DEFKIFTNIN 70 80 90 100 110 120 SSIVDPKAFD ARSFVDVKSD VCIIPPNSFA LARTVEYFRI PRSVLTICLG KSTYARCGII 130 140 150 160 170 180 VNVTPLEPEW EGHVTLEFSN TTPLPAKIYA NEGVAQMLFL ESDEVCETSY KDRGGKYQGQ VGVTLPKT

References

[1]

"Complete genome sequence of 'Thioalkalivibrio sulfidophilus' HL-EbGr7." Muyzer G., Sorokin D.Y., Mavromatis K., Lapidus A., Clum A., Ivanova N., Pati A., d'Haeseleer P., Woyke T., Kyrpides N.C. Stand. Genomic Sci. 4:23-35(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HL-EbGR7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001339 Genomic DNA. Translation: ACL73695.1.
RefSeq	YP_002514682.1. NC_011901.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	396588.Tgr7_2620.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL73695; ACL73695; Tgr7_2620.
GeneID	7315339.
KEGG	tgr:Tgr7_2620.
PATRIC	23964756. VBIThiSp19295_2599.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
KO	K01494.
OMA	RSVLTVC.
ProtClustDB	CLSK2546547.
Enzyme and pathway databases
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_THISH

Accession

Primary (citable) accession number: B8GMA8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program