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Protein

Cytidylate kinase

Gene

cmk

Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (d)CMP = ADP + (d)CDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 159ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPAL521011:GI2F-478-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cytidylate kinaseUniRule annotation (EC:2.7.4.25UniRule annotation)
Short name:
CKUniRule annotation
Alternative name(s):
Cytidine monophosphate kinaseUniRule annotation
Short name:
CMP kinaseUniRule annotation
Gene namesi
Name:cmkUniRule annotation
Ordered Locus Names:Mpal_0468
OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Taxonomic identifieri521011 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
Proteomesi
  • UP000002457 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 176176Cytidylate kinasePRO_1000125312Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi521011.Mpal_0468.

Structurei

3D structure databases

ProteinModelPortaliB8GKF9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytidylate kinase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01037. Archaea.
COG1102. LUCA.
HOGENOMiHOG000105913.
KOiK00945.
OMAiYTPLEFN.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00239. Cytidyl_kinase_type2.
InterProiIPR026865. Cmk2-like.
IPR011892. Cyt_kin_arch.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13189. Cytidylate_kin2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02173. cyt_kin_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

B8GKF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRITISGPPG SGTTSLSKHL AAEHNLKLIS AGEVFRQLAR EKGMDLAAFG
60 70 80 90 100
ELAENDPSID LMIDARQKQI ATEQDDIIVE GRLSGRMVEQ ADLRIWLNAP
110 120 130 140 150
LTCRVGRIAF RDSVTCEEEA MTLTREREAS EAKRYMMYYQ IDISDLSSYH
160 170
LVLNTERWSV GQLGLIVNCA IAAVRD
Length:176
Mass (Da):19,628
Last modified:March 3, 2009 - v1
Checksum:i8E30E6EEFBAA3F81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001338 Genomic DNA. Translation: ACL15842.1.
RefSeqiWP_012617161.1. NC_011832.1.

Genome annotation databases

EnsemblBacteriaiACL15842; ACL15842; Mpal_0468.
GeneIDi7272792.
KEGGimpl:Mpal_0468.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001338 Genomic DNA. Translation: ACL15842.1.
RefSeqiWP_012617161.1. NC_011832.1.

3D structure databases

ProteinModelPortaliB8GKF9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi521011.Mpal_0468.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL15842; ACL15842; Mpal_0468.
GeneIDi7272792.
KEGGimpl:Mpal_0468.

Phylogenomic databases

eggNOGiarCOG01037. Archaea.
COG1102. LUCA.
HOGENOMiHOG000105913.
KOiK00945.
OMAiYTPLEFN.

Enzyme and pathway databases

BioCyciMPAL521011:GI2F-478-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00239. Cytidyl_kinase_type2.
InterProiIPR026865. Cmk2-like.
IPR011892. Cyt_kin_arch.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF13189. Cytidylate_kin2. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR02173. cyt_kin_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Candidatus Methanosphaerula E1-9c."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Entry informationi

Entry nameiKCY_METPE
AccessioniPrimary (citable) accession number: B8GKF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: November 11, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.