B8GJX0 (B8GJX0_METPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase RuleBase RU004370
EC=6.3.3.1 RuleBase RU004370

Gene names

Ordered Locus Names:

Mpal_0400

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) [Complete proteome] [HAMAP]

Taxonomic identifier

521011 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanosphaerula

Protein attributes

Sequence length	330 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. RuleBase RU004370
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. RuleBase RU004371
Sequence similarities	Belongs to the AIR synthase family. RuleBase RU004370

Ontologies

Keywords
Molecular function	Ligase RuleBase RU004370 EMBL ACL15774.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	phosphoribosylformylglycinamidine cyclo-ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8GJX0 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: EF0BB1FB42E922A3	FASTA	330	35,241
	10 20 30 40 50 60 MSEHAYRDAG VDIDLEAAAV KALIGQLSFR RQGSYPMLGK VGHFAGLIDF GPVALALAVD 70 80 90 100 110 120 GVGTKMLIAD HQQNWKTVGI DCIAMNVNDL YVMNLEPIAF VDYIATDRLS LEKMTEIGIG 130 140 150 160 170 180 LNEGARQANM NIVGGETASL AGLVNGLDLA GACLGVQQKE RIISGEAIRP GDLVIGVPST 190 200 210 220 230 240 GVHSNGLSLA RRIAETHDGY DQEIRPGRTL GEELLTPTRI YAEVPAITAA HEVHGMCHIT 250 260 270 280 290 300 GGGLLNFTRL SRFGIAITDP LPPQQVFTWL QETGEVSEVE MYRTFNMGMG YALVIPPDAA 310 320 330 DGVVRDLPGS KIVGSCTEEA KITLCGTEIR

References

[1]

"Complete sequence of Candidatus Methanosphaerula E1-9c." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001338 Genomic DNA. Translation: ACL15774.1.
RefSeq	YP_002465497.1. NC_011832.1.
3D structure databases
ProteinModelPortal	B8GJX0.
ModBase	Search...
Protein-protein interaction databases
STRING	B8GJX0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7271426.
GenomeReviews	Gene locus Mpal_0400 in contig CP001338_GR.
KEGG	mpl:Mpal_0400.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG531222.
OMA	GIDMIAM.
ProtClustDB	CLSK949966.
Family and domain databases
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view]
KO	K01933.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00878. PurM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8GJX0_METPE

Accession

Primary (citable) accession number: B8GJX0

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	November 16, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)