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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mpal_0288
OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Taxonomic identifieri521011 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
Proteomesi
  • UP000002457 Componenti: Chromosome

Subcellular locationi

B8GJL7:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001989431 – 559Arginine--tRNA ligaseAdd BLAST559

Interactioni

Protein-protein interaction databases

STRINGi521011.Mpal_0288.

Structurei

3D structure databases

ProteinModelPortaliB8GJL7.
SMRiB8GJL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi116 – 126"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487. Archaea.
COG0018. LUCA.
HOGENOMiHOG000247213.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG093Z013U.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B8GJL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTETYTLIE RVLKACTDET EIALTDGGEH ADLASTVAFA LAKKRHQAPK
60 70 80 90 100
VIAEELAVTL AANPELAGIR VEALGPYLNF SFGPKYLEET LKAAVQDNFG
110 120 130 140 150
TAPTKPVRIV LEHTSANPNG PLHVGHIRNS ILGDTLARAF RKAGYRVEVQ
160 170 180 190 200
YYVNDMGRQI AIVAYGFDHL DTGAKPGEKA DHHIARVYVA ANRDLEANPD
210 220 230 240 250
KGAEIDERMQ LIEKRDPATA TQFRELVSRC LDGFKVTMQG LNVKHDRFIW
260 270 280 290 300
ESDFVKIGDM EKVLGRLAKI PQAVPPTEED GTFSLDLSSC GYKKSYVLRR
310 320 330 340 350
SDGTSVYAAR DLAYHIWKGR NFDRVIDVLG ADHKLITGQL VCTLRLIAEK
360 370 380 390 400
PPEVVHFEFV SLPEGSMSTR AGTFVSADEL IEEMQKRAIE EVQVRRPEIP
410 420 430 440 450
VEERDAIAAS VARAAIRYDI IKVSPEKSTV FDWKEALDFD RQSGPYVQYA
460 470 480 490 500
HARACSILDR AGPFQERYDL LESPYEIALV KHIAKFPSII ESVVRDLRPH
510 520 530 540 550
MLATYARDLA DLFNTFYHYD PVLKGEGPVR ESRLTLVLAA EKTLKEVLET

LGIDALRSM
Length:559
Mass (Da):62,498
Last modified:March 3, 2009 - v1
Checksum:i496BEEA1F56573D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001338 Genomic DNA. Translation: ACL15671.1.
RefSeqiWP_012616990.1. NC_011832.1.

Genome annotation databases

EnsemblBacteriaiACL15671; ACL15671; Mpal_0288.
GeneIDi7272588.
KEGGimpl:Mpal_0288.

Similar proteinsi

Entry informationi

Entry nameiSYR_METPE
AccessioniPrimary (citable) accession number: B8GJL7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: October 25, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families