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B8GGC7

- B8GGC7_METPE

UniProt

B8GGC7 - B8GGC7_METPE

Protein

Glyceraldehyde-3-phosphate dehydrogenase

Gene

gap

Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei110 – 1101NAD; via amide nitrogenUniRule annotation
    Active sitei140 – 1401NucleophileUniRule annotation
    Binding sitei168 – 1681NADUniRule annotation
    Binding sitei302 – 3021NAD; via carbonyl oxygenUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi11 – 122NADUniRule annotation

    GO - Molecular functioni

    1. glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Source: UniProtKB-EC
    2. glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: UniProtKB-HAMAP
    3. NAD binding Source: InterPro
    4. NADP binding Source: InterPro

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    NADUniRule annotationSAAS annotation, NADPUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMPAL521011:GI2F-2860-MONOMER.
    UniPathwayiUPA00109; UER00184.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.59UniRule annotation)
    Short name:
    GAPDHUniRule annotation
    Alternative name(s):
    NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation
    Gene namesi
    Name:gapUniRule annotation
    Ordered Locus Names:Mpal_2790Imported
    OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)Imported
    Taxonomic identifieri521011 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
    ProteomesiUP000002457: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi521011.Mpal_2790.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni139 – 1413Glyceraldehyde 3-phosphate bindingUniRule annotation
    Regioni194 – 1952Glyceraldehyde 3-phosphate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0057.
    HOGENOMiHOG000223361.
    KOiK00150.
    OMAiVTVPSHH.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00559. G3P_dehdrog_arch.
    InterProiIPR020831. GlycerAld/Erythrose_P_DH.
    IPR020830. GlycerAld_3-P_DH_AS.
    IPR020829. GlycerAld_3-P_DH_cat.
    IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
    IPR006436. Glyceraldehyde-3-P_DH_2_arc.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF02800. Gp_dh_C. 1 hit.
    PF00044. Gp_dh_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000149. GAP_DH. 1 hit.
    SMARTiSM00846. Gp_dh_N. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01546. GAPDH-II_archae. 1 hit.
    PROSITEiPS00071. GAPDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8GGC7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKVAINGYG TIGKRVADAV AAQPDMEIIG VSKTSPSAEA FVAQSRGYPL    50
    YIADIGRKPD FEKAGIRVAG SVEEMLTRAD VVVDATPGGV GAKNKPLYEK 100
    LGVRVIYQGG EKHLLAGFSF NSSCNYAKAI GRQFVRVVSC NTTGLCRIIH 150
    LVDTAYGVKK VRATMIRRAS DPGEIKRGPV DAIVLDPVTV PSHHGPDVQS 200
    VLPTIPITTA ALIVPTTFMH MHVVMIETEK EADREEIIQL IESHPRLGLV 250
    RPATGITSTA QLKEYMQDLG RSRADLWENG IFQDSVSVVD GHEVCLYQAI 300
    HQEADVVVEN VDAIRAMIGE VTDAETSIAI TNKALGFTAI 340
    Length:340
    Mass (Da):36,659
    Last modified:March 3, 2009 - v1
    Checksum:i791C9B85CB444A52
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001338 Genomic DNA. Translation: ACL18045.1.
    RefSeqiWP_012619364.1. NC_011832.1.
    YP_002467768.1. NC_011832.1.

    Genome annotation databases

    EnsemblBacteriaiACL18045; ACL18045; Mpal_2790.
    GeneIDi7271376.
    KEGGimpl:Mpal_2790.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001338 Genomic DNA. Translation: ACL18045.1 .
    RefSeqi WP_012619364.1. NC_011832.1.
    YP_002467768.1. NC_011832.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 521011.Mpal_2790.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL18045 ; ACL18045 ; Mpal_2790 .
    GeneIDi 7271376.
    KEGGi mpl:Mpal_2790.

    Phylogenomic databases

    eggNOGi COG0057.
    HOGENOMi HOG000223361.
    KOi K00150.
    OMAi VTVPSHH.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00184 .
    BioCyci MPAL521011:GI2F-2860-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00559. G3P_dehdrog_arch.
    InterProi IPR020831. GlycerAld/Erythrose_P_DH.
    IPR020830. GlycerAld_3-P_DH_AS.
    IPR020829. GlycerAld_3-P_DH_cat.
    IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
    IPR006436. Glyceraldehyde-3-P_DH_2_arc.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF02800. Gp_dh_C. 1 hit.
    PF00044. Gp_dh_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000149. GAP_DH. 1 hit.
    SMARTi SM00846. Gp_dh_N. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01546. GAPDH-II_archae. 1 hit.
    PROSITEi PS00071. GAPDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Candidatus Methanosphaerula E1-9c."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S.
      Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1556 / DSM 19958 / E1-9cImported.

    Entry informationi

    Entry nameiB8GGC7_METPE
    AccessioniPrimary (citable) accession number: B8GGC7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3