Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B8GGC7

- B8GGC7_METPE

UniProt

B8GGC7 - B8GGC7_METPE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glyceraldehyde-3-phosphate dehydrogenase

Gene

gap

Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei110 – 1101NAD; via amide nitrogenUniRule annotation
Active sitei140 – 1401NucleophileUniRule annotation
Binding sitei168 – 1681NADUniRule annotation
Binding sitei302 – 3021NAD; via carbonyl oxygenUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 122NADUniRule annotation

GO - Molecular functioni

  1. glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Source: UniProtKB-EC
  2. glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: UniProtKB-HAMAP
  3. NAD binding Source: InterPro
  4. NADP binding Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotation

Keywords - Biological processi

GlycolysisUniRule annotation

Keywords - Ligandi

NADUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciMPAL521011:GI2F-2860-MONOMER.
UniPathwayiUPA00109; UER00184.

Names & Taxonomyi

Protein namesi
Recommended name:
Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.59UniRule annotation)
Short name:
GAPDHUniRule annotation
Alternative name(s):
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation
Gene namesi
Name:gapUniRule annotation
Ordered Locus Names:Mpal_2790Imported
OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)Imported
Taxonomic identifieri521011 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
ProteomesiUP000002457: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi521011.Mpal_2790.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni139 – 1413Glyceraldehyde 3-phosphate bindingUniRule annotation
Regioni194 – 1952Glyceraldehyde 3-phosphate bindingUniRule annotation

Sequence similaritiesi

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0057.
HOGENOMiHOG000223361.
KOiK00150.
OMAiVTVPSHH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00559. G3P_dehdrog_arch.
InterProiIPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000149. GAP_DH. 1 hit.
SMARTiSM00846. Gp_dh_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01546. GAPDH-II_archae. 1 hit.
PROSITEiPS00071. GAPDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8GGC7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIKVAINGYG TIGKRVADAV AAQPDMEIIG VSKTSPSAEA FVAQSRGYPL
60 70 80 90 100
YIADIGRKPD FEKAGIRVAG SVEEMLTRAD VVVDATPGGV GAKNKPLYEK
110 120 130 140 150
LGVRVIYQGG EKHLLAGFSF NSSCNYAKAI GRQFVRVVSC NTTGLCRIIH
160 170 180 190 200
LVDTAYGVKK VRATMIRRAS DPGEIKRGPV DAIVLDPVTV PSHHGPDVQS
210 220 230 240 250
VLPTIPITTA ALIVPTTFMH MHVVMIETEK EADREEIIQL IESHPRLGLV
260 270 280 290 300
RPATGITSTA QLKEYMQDLG RSRADLWENG IFQDSVSVVD GHEVCLYQAI
310 320 330 340
HQEADVVVEN VDAIRAMIGE VTDAETSIAI TNKALGFTAI
Length:340
Mass (Da):36,659
Last modified:March 3, 2009 - v1
Checksum:i791C9B85CB444A52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001338 Genomic DNA. Translation: ACL18045.1.
RefSeqiYP_002467768.1. NC_011832.1.

Genome annotation databases

EnsemblBacteriaiACL18045; ACL18045; Mpal_2790.
GeneIDi7271376.
KEGGimpl:Mpal_2790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001338 Genomic DNA. Translation: ACL18045.1 .
RefSeqi YP_002467768.1. NC_011832.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 521011.Mpal_2790.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL18045 ; ACL18045 ; Mpal_2790 .
GeneIDi 7271376.
KEGGi mpl:Mpal_2790.

Phylogenomic databases

eggNOGi COG0057.
HOGENOMi HOG000223361.
KOi K00150.
OMAi VTVPSHH.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00184 .
BioCyci MPAL521011:GI2F-2860-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00559. G3P_dehdrog_arch.
InterProi IPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000149. GAP_DH. 1 hit.
SMARTi SM00846. Gp_dh_N. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01546. GAPDH-II_archae. 1 hit.
PROSITEi PS00071. GAPDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Candidatus Methanosphaerula E1-9c."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1556 / DSM 19958 / E1-9cImported.

Entry informationi

Entry nameiB8GGC7_METPE
AccessioniPrimary (citable) accession number: B8GGC7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 26, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3