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B8GGC7

- B8GGC7_METPE

UniProt

B8GGC7 - B8GGC7_METPE

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Protein

Glyceraldehyde-3-phosphate dehydrogenase

Gene
gap, Mpal_2790
Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei110 – 1101NAD; via amide nitrogen By similarityUniRule annotation
Active sitei140 – 1401Nucleophile By similarityUniRule annotation
Binding sitei168 – 1681NAD By similarityUniRule annotation
Binding sitei302 – 3021NAD; via carbonyl oxygen By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 122NAD By similarityUniRule annotation

GO - Molecular functioni

  1. glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Source: UniProtKB-EC
  2. glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: UniProtKB-HAMAP
  3. NAD binding Source: InterPro
  4. NADP binding Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

NADUniRule annotationSAAS annotations, NADPUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciMPAL521011:GI2F-2860-MONOMER.
UniPathwayiUPA00109; UER00184.

Names & Taxonomyi

Protein namesi
Recommended name:
Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.59UniRule annotation)
Short name:
GAPDHUniRule annotation
Alternative name(s):
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene namesi
Name:gapUniRule annotation
Ordered Locus Names:Mpal_2790Imported
OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)Imported
Taxonomic identifieri521011 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
ProteomesiUP000002457: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Protein-protein interaction databases

STRINGi521011.Mpal_2790.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni139 – 1413Glyceraldehyde 3-phosphate binding By similarityUniRule annotation
Regioni194 – 1952Glyceraldehyde 3-phosphate binding By similarityUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0057.
HOGENOMiHOG000223361.
KOiK00150.
OMAiVTVPSHH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00559. G3P_dehdrog_arch.
InterProiIPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000149. GAP_DH. 1 hit.
SMARTiSM00846. Gp_dh_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01546. GAPDH-II_archae. 1 hit.
PROSITEiPS00071. GAPDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8GGC7-1 [UniParc]FASTAAdd to Basket

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MIKVAINGYG TIGKRVADAV AAQPDMEIIG VSKTSPSAEA FVAQSRGYPL    50
YIADIGRKPD FEKAGIRVAG SVEEMLTRAD VVVDATPGGV GAKNKPLYEK 100
LGVRVIYQGG EKHLLAGFSF NSSCNYAKAI GRQFVRVVSC NTTGLCRIIH 150
LVDTAYGVKK VRATMIRRAS DPGEIKRGPV DAIVLDPVTV PSHHGPDVQS 200
VLPTIPITTA ALIVPTTFMH MHVVMIETEK EADREEIIQL IESHPRLGLV 250
RPATGITSTA QLKEYMQDLG RSRADLWENG IFQDSVSVVD GHEVCLYQAI 300
HQEADVVVEN VDAIRAMIGE VTDAETSIAI TNKALGFTAI 340
Length:340
Mass (Da):36,659
Last modified:March 3, 2009 - v1
Checksum:i791C9B85CB444A52
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001338 Genomic DNA. Translation: ACL18045.1.
RefSeqiWP_012619364.1. NC_011832.1.
YP_002467768.1. NC_011832.1.

Genome annotation databases

EnsemblBacteriaiACL18045; ACL18045; Mpal_2790.
GeneIDi7271376.
KEGGimpl:Mpal_2790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001338 Genomic DNA. Translation: ACL18045.1 .
RefSeqi WP_012619364.1. NC_011832.1.
YP_002467768.1. NC_011832.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 521011.Mpal_2790.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL18045 ; ACL18045 ; Mpal_2790 .
GeneIDi 7271376.
KEGGi mpl:Mpal_2790.

Phylogenomic databases

eggNOGi COG0057.
HOGENOMi HOG000223361.
KOi K00150.
OMAi VTVPSHH.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00184 .
BioCyci MPAL521011:GI2F-2860-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00559. G3P_dehdrog_arch.
InterProi IPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000149. GAP_DH. 1 hit.
SMARTi SM00846. Gp_dh_N. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01546. GAPDH-II_archae. 1 hit.
PROSITEi PS00071. GAPDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Candidatus Methanosphaerula E1-9c."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Entry informationi

Entry nameiB8GGC7_METPE
AccessioniPrimary (citable) accession number: B8GGC7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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