B8GG86 (B8GG86_METPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
Short name=FBPase class 1 HAMAP MF_01855
EC=3.1.3.11 HAMAP MF_01855

Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 HAMAP MF_01855

Gene names

Name:	fbp HAMAP MF_01855
Ordered Locus Names:	Mpal_0798

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) [Complete proteome] [HAMAP]

Taxonomic identifier

521011 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanosphaerula

Protein attributes

Sequence length	298 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm By similarity HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family. HAMAP MF_01855 RuleBase RU000508

Ontologies

Keywords
Biological process	Carbohydrate metabolism HAMAP MF_01855 RuleBase RU000508
Cellular component	Cytoplasm HAMAP MF_01855
Ligand	Magnesium HAMAP MF_01855 Metal-binding HAMAP MF_01855
Molecular function	Hydrolase HAMAP MF_01855 RuleBase RU000508
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	102 – 105	4	Substrate binding By similarity HAMAP MF_01855
Sites
	Metal binding	79	1	Magnesium 1 By similarity HAMAP MF_01855
	Metal binding	99	1	Magnesium 1 By similarity HAMAP MF_01855
	Metal binding	99	1	Magnesium 2 By similarity HAMAP MF_01855
	Metal binding	101	1	Magnesium 1; via carbonyl oxygen By similarity HAMAP MF_01855
	Metal binding	102	1	Magnesium 2 By similarity HAMAP MF_01855
	Metal binding	245	1	Magnesium 2 By similarity HAMAP MF_01855
	Binding site	209	1	Substrate By similarity HAMAP MF_01855
	Binding site	239	1	Substrate By similarity HAMAP MF_01855

Sequences

	Sequence		Length	Mass (Da)
	B8GG86 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: A123996EB0A36C59	FASTA	298	32,760
	10 20 30 40 50 60 MITLEEYLDG TGAEQELKEL VRLIAAQATP IREAFLTNQT YAGTTNQSGE EQAAMDTWAD 70 80 90 100 110 120 RHITEVLQRS GLVREVASEE QNDILKIPES HGEYAVVMDP LDGSSLIQVN LAVGTIVGIY 130 140 150 160 170 180 DHGTVMQPGE KMRAALYMLY GPMTVLTLTV GEGVQIFALD NNNQYVLLEA DVKMPEGNLY 190 200 210 220 230 240 GSGGLRTVWT EEHARFIDTC EQEGYKLRYS GSFVADFHQI LKYGGIYCYP AVVGKERGKL 250 260 270 280 290 RLMFEANPIG FIATQAGGAI CDGRMNVLTI NPEKPHQKTP LYVGSKGLIE KVNGTLCT

References

[1]

"Complete sequence of Candidatus Methanosphaerula E1-9c." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001338 Genomic DNA. Translation: ACL16160.1.
RefSeq	YP_002465883.1. NC_011832.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8GG86.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7270539.
GenomeReviews	Gene locus Mpal_0798 in contig CP001338_GR.
KEGG	mpl:Mpal_0798.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG731261.
OMA	RNTDGDV.
ProtClustDB	CLSK949627.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. FBPase_class-1/SBPase. [Graphical view]
KO	K03841.
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PIRSF	PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTS	PR00115. F16BPHPHTASE.
ProtoNet	Search...

Entry information

Entry name

B8GG86_METPE

Accession

Primary (citable) accession number: B8GG86

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)