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Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Enzyme and pathway databases

BioCyciMPAL521011:G1GUJ-818-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:Mpal_0792
OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Taxonomic identifieri521011 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
Proteomesi
  • UP000002457 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001329711 – 247DNA polymerase sliding clampAdd BLAST247

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi521011.Mpal_0792

Structurei

3D structure databases

ProteinModelPortaliB8GG80
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
HOGENOMiHOG000222371
KOiK04802
OMAiSDGFDKY
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN

Sequencei

Sequence statusi: Complete.

B8GG80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDATIDADV FRESVDAIAA LVTECRLHAT EQGLRTRTVD TANVAMISLE
60 70 80 90 100
LDKDVFESYQ ATSSEMGIDI VKIKNVLSMM GKGDPVHLAL AEESRKLEVS
110 120 130 140 150
FQSYQYSITL LDTNTIRKDP NAPTIELPGK VVISGAALSA AIKAASVVSD
160 170 180 190 200
KIALGIDPEK GIFYMEAEGD TDHIRLELGD DKLISLVPVQ ARSLFSLDYL
210 220 230 240
KDMGKTMSKA EKVEISLGID HPVEFTFDIA DGKGHVMYLL APRIEAD
Length:247
Mass (Da):26,920
Last modified:March 3, 2009 - v1
Checksum:iF4D7167796041AFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001338 Genomic DNA Translation: ACL16154.1
RefSeqiWP_012617473.1, NC_011832.1

Genome annotation databases

EnsemblBacteriaiACL16154; ACL16154; Mpal_0792
GeneIDi7270533
KEGGimpl:Mpal_0792

Similar proteinsi

Entry informationi

Entry nameiPCNA_METPE
AccessioniPrimary (citable) accession number: B8GG80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome