B8GFN7 (APGM_METPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Mpal_2656

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) [Complete proteome] [HAMAP]

Taxonomic identifier

521011 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanosphaerula

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_1000184574

Sequences

	Sequence		Length	Mass (Da)
	B8GFN7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 66B09742B17D6AE4	FASTA	411	43,261
	10 20 30 40 50 60 MTAHKIVMLV LDGIGDRPCG ELAGMTPLQA AKTPILDQLA AEGITGIMDT IGPGIRPGSD 70 80 90 100 110 120 TSHLSLLGYP PESYYTGRGP LEAEGCGIHM EHGMIGFRAN FATQNDHGLV TDRRAGRIHD 130 140 150 160 170 180 TRLLSAAITD QVDLSAFGVT FSFASGAGHR AALALSGEGL GAGVTSNDPK EDGVAPHQVM 190 200 210 220 230 240 PVSANPEDQK TAAVCNEFIR QSTAILADHP MNRARVLNGE SPASVVLIRG AGEMGGFEPF 250 260 270 280 290 300 QQRYDLSGAV IAAATLVTGI GKAVGLEYIP VEGVTGSTTT NLTGKVQTLM ATLDTHDFVL 310 320 330 340 350 360 LNIKGADEAG HDGHAIEKRD FIERIDAALA LLLERNDCII AVMGDHSTPC PIKEHSADPV 370 380 390 400 410 PVLIRGDGVR VDLVQAYDEI ACAAGGLNRI RGADILWILL DLIDKTHKYG T

References

[1]

"Complete sequence of Candidatus Methanosphaerula E1-9c." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001338 Genomic DNA. Translation: ACL17920.1.
RefSeq	YP_002467643.1. NC_011832.1.
3D structure databases
ProteinModelPortal	B8GFN7.
ModBase	Search...
Protein-protein interaction databases
STRING	B8GFN7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7272478.
GenomeReviews	Gene locus Mpal_2656 in contig CP001338_GR.
KEGG	mpl:Mpal_2656.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	CLSK734628.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_METPE

Accession

Primary (citable) accession number: B8GFN7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program