B8GFA5 (B8GFA5_METPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE HAMAP MF_00060
EC=3.1.3.5 HAMAP MF_00060

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase HAMAP MF_00060

Gene names

Name:	surE HAMAP MF_00060
Ordered Locus Names:	Mpal_0582

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) [Complete proteome] [HAMAP]

Taxonomic identifier

521011 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanosphaerula

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity. HAMAP MF_00060
Subcellular location	Cytoplasm By similarity HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family. HAMAP MF_00060

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00060
Ligand	Metal-binding HAMAP MF_00060 Nucleotide-binding HAMAP MF_00060
Molecular function	Hydrolase HAMAP MF_00060 EMBL ACL15953.1
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	11	1	Divalent metal cation By similarity HAMAP MF_00060
	Metal binding	12	1	Divalent metal cation By similarity HAMAP MF_00060
	Metal binding	42	1	Divalent metal cation By similarity HAMAP MF_00060
	Metal binding	96	1	Divalent metal cation By similarity HAMAP MF_00060

Sequences

	Sequence		Length	Mass (Da)
	B8GFA5 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: B8F5F02C651A2A50	FASTA	263	28,302
	10 20 30 40 50 60 MKKPRVLLTN DDGINSVGLW AAYEALSDIC EVTVVAPASQ QSAVGRSISI FEPIRAGMVS 70 80 90 100 110 120 MHGISAYAVG GKPTDAVIIG LYALDLKPDL VVSGINIGEN LSYESIMTSG TVGAALEAAN 130 140 150 160 170 180 QGTPAVAFSL QVEDQGDKFD DPRRPSQSFS SAKQVVRDVC SRIFEQGFPQ STDVINVNVP 190 200 210 220 230 240 SMIRGGYVVT RLAKKLFRTG VEKRLDPRGR PYFWINGPLL DDAEEGTDFH AIKSGAISIT 250 260 PITLDCTATW AVDDMSRLFS LEK

References

[1]

"Complete sequence of Candidatus Methanosphaerula E1-9c." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001338 Genomic DNA. Translation: ACL15953.1.
RefSeq	YP_002465676.1. NC_011832.1.
3D structure databases
ProteinModelPortal	B8GFA5.
ModBase	Search...
Protein-protein interaction databases
STRING	B8GFA5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7270166.
GenomeReviews	Gene locus Mpal_0582 in contig CP001338_GR.
KEGG	mpl:Mpal_0582.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	NGFYYVN.
ProtClustDB	PRK00346.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8GFA5_METPE

Accession

Primary (citable) accession number: B8GFA5

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	November 16, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)