B8GF67 (B8GF67_METPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-dehydroquinate dehydratase HAMAP MF_00214
Short name=3-dehydroquinase HAMAP MF_00214
EC=4.2.1.10 HAMAP MF_00214

Alternative name(s):
Type I DHQase HAMAP MF_00214

Gene names

Name:	aroD HAMAP MF_00214
Ordered Locus Names:	Mpal_2603

Organism

Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) [Complete proteome] [HAMAP]

Taxonomic identifier

521011 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanosphaerula

Protein attributes

Sequence length	197 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214
Sequence similarities	Belongs to the type-I 3-dehydroquinase family. HAMAP MF_00214

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00214
Ligand	Schiff base HAMAP MF_00214
Molecular function	Lyase HAMAP MF_00214
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	3-dehydroquinate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	97	1	Proton acceptor By similarity HAMAP MF_00214
	Active site	122	1	Schiff-base intermediate with substrate By similarity HAMAP MF_00214

Sequences

	Sequence		Length	Mass (Da)
	B8GF67 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 68D81334FE2C25F9	FASTA	197	21,427
	10 20 30 40 50 60 MPLAAASGAD LIEIRLDLFP TADLENLPAL LREVSLPLIV TVRSRAEGGR FTGGPEEWRA 70 80 90 100 110 120 LVTPYLPVAR YVDIEQRFSS CAPAIRAAGV KVIASFHTPT ILKEDELVAI EARLRTFGDL 130 140 150 160 170 180 PKIVTGVGTR DDLLTLLQFT SSRTAPICTS IMGEQCRFGR GLLPLFSSML VYCYITTPAS 190 AGQYPVGEMR TILSLLT

References

[1]

"Complete sequence of Candidatus Methanosphaerula E1-9c." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001338 Genomic DNA. Translation: ACL17873.1.
RefSeq	YP_002467596.1. NC_011832.1.
3D structure databases
ProteinModelPortal	B8GF67.
ModBase	Search...
Protein-protein interaction databases
STRING	B8GF67.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7271871.
GenomeReviews	Gene locus Mpal_2603 in contig CP001338_GR.
KEGG	mpl:Mpal_2603.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG541552.
OMA	PICTSIM.
ProtClustDB	CLSK949565.
Family and domain databases
HAMAP	MF_00214. AroD. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001381. DHquinase_I. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K03785.
Pfam	PF01487. DHquinase_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8GF67_METPE

Accession

Primary (citable) accession number: B8GF67

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	November 16, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)