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B8GET9

- RNP4_METPE

UniProt

B8GET9 - RNP4_METPE

Protein

Ribonuclease P protein component 4

Gene

rnp4

Organism
Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi63 – 631ZincUniRule annotation
    Metal bindingi66 – 661ZincUniRule annotation
    Metal bindingi89 – 891ZincUniRule annotation
    Metal bindingi92 – 921ZincUniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciMPAL521011:GI2F-545-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein component 4UniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P component 4UniRule annotation
    Alternative name(s):
    Rpp21UniRule annotation
    Gene namesi
    Name:rnp4UniRule annotation
    Ordered Locus Names:Mpal_0533
    OrganismiMethanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c)
    Taxonomic identifieri521011 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanosphaerula
    ProteomesiUP000002457: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. ribonuclease P complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 106106Ribonuclease P protein component 4PRO_1000148373Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi521011.Mpal_0533.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic/archaeal RNase P protein component 4 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2023.
    HOGENOMiHOG000230709.
    KOiK03540.
    OMAiVIVTCLN.

    Family and domain databases

    HAMAPiMF_00757. RNase_P_4.
    InterProiIPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view]
    PfamiPF04032. Rpr2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004878. RNase_P_4. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B8GET9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTVKSQNRQT KKLAGERIAI LFTQAKVFAG INPAWSDRCV ERARAIAMRQ    50
    RMRMEREQRR QYCHHCYAYF LHGVNVRVRV HRGHVIVTCL NCGRQTRYQV 100
    VRTDNR 106
    Length:106
    Mass (Da):12,603
    Last modified:March 3, 2009 - v1
    Checksum:i32EC60A25A511EB1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001338 Genomic DNA. Translation: ACL15906.1.
    RefSeqiYP_002465629.1. NC_011832.1.

    Genome annotation databases

    EnsemblBacteriaiACL15906; ACL15906; Mpal_0533.
    GeneIDi7271949.
    KEGGimpl:Mpal_0533.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001338 Genomic DNA. Translation: ACL15906.1 .
    RefSeqi YP_002465629.1. NC_011832.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 521011.Mpal_0533.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL15906 ; ACL15906 ; Mpal_0533 .
    GeneIDi 7271949.
    KEGGi mpl:Mpal_0533.

    Phylogenomic databases

    eggNOGi COG2023.
    HOGENOMi HOG000230709.
    KOi K03540.
    OMAi VIVTCLN.

    Enzyme and pathway databases

    BioCyci MPAL521011:GI2F-545-MONOMER.

    Family and domain databases

    HAMAPi MF_00757. RNase_P_4.
    InterProi IPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view ]
    Pfami PF04032. Rpr2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004878. RNase_P_4. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Candidatus Methanosphaerula E1-9c."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Lu M., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.O., Zinder S.
      Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1556 / DSM 19958 / E1-9c.

    Entry informationi

    Entry nameiRNP4_METPE
    AccessioniPrimary (citable) accession number: B8GET9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3