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B8G9U9 (B8G9U9_CHLAD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase HAMAP MF_00110

EC=4.2.3.4 HAMAP MF_00110
Gene names
Name:aroB HAMAP MF_00110
Ordered Locus Names:Cagg_1562
OrganismChloroflexus aggregans (strain MD-66 / DSM 9485) [Complete proteome] [HAMAP] EMBL ACL24464.1
Taxonomic identifier326427 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeChloroflexus

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00110
   Cellular componentCytoplasm HAMAP MF_00110
   LigandNAD HAMAP MF_00110
   Molecular functionLyase HAMAP MF_00110 EMBL ACL24464.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B8G9U9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: B0BB64CDCAF68394

FASTA38540,934
        10         20         30         40         50         60 
MIAPLKDSSI VMTTTLTVTT STTQYPVIVG AGVLATLGDR LTELGLRGTL WLVADEHLAA 

        70         80         90        100        110        120 
VAEQTTTMLQ AAGYRVHTIT VPSGETSKSF TELHRLYDWM IENGIERRDA VLALGGGVIG 

       130        140        150        160        170        180 
DLAGFAAATI LRGVALVQLP STLLAMVDAA VGGKTGINHP LGKNLIGAFH QPRLVLADTN 

       190        200        210        220        230        240 
LLATLPPREL RAGWAEVIKH GVIRDASLFT ALEDLAATRG WNAAHPAGWN AADAELTTYL 

       250        260        270        280        290        300 
TEIIARAVAV KVAVVSNDEF ERGERITLNY GHTIGHAIEQ LLGYRLLHGE CVAIGMDAAA 

       310        320        330        340        350        360 
RIAVALGLCP PALVERQRAL LAAYGLTVTI PDETDHTAIL RLITRDKKVQ AGKVRWVLPT 

       370        380 
TIGQVVVRSD VPIEVIEQVL SSSAG 

« Hide

References

[1]"Complete sequence of Chloroflexus aggregans DSM 9485."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MD-66 / DSM 9485.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001337 Genomic DNA. Translation: ACL24464.1.
RefSeqYP_002462900.1. NC_011831.1.

3D structure databases

ProteinModelPortalB8G9U9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8G9U9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7267339.
GenomeReviewsGene locus Cagg_1562 in contig CP001337_GR.
KEGGcag:Cagg_1562.
PATRIC21405646. VBIChlAgg85409_1612.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAVMALEMS.
ProtClustDBCLSK975397.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8G9U9_CHLAD
AccessionPrimary (citable) accession number: B8G9U9
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)