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B8G814 (B8G814_CHLAD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
Short name=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF HAMAP MF_01840
Ordered Locus Names:Cagg_1285
OrganismChloroflexus aggregans (strain MD-66 / DSM 9485) [Complete proteome] [HAMAP] EMBL ACL24193.1
Taxonomic identifier326427 [NCBI]
Taxonomic lineageBacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length375 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; bacteriochlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B8G814 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 7AD23570C313ACBA

FASTA37544,976
        10         20         30         40         50         60 
MFWINPLMME MPGEFSRTTR HALKEAILSP RFYTTDFKAI DKLEIDRNGL RDEFDWIRDE 

        70         80         90        100        110        120 
FAYDYNRTHF RRTDEFLQNF DDMPERDAFI DFLERSCTAE FSGCLLYAEM VKHLHDPTLR 

       130        140        150        160        170        180 
AIFKYMSRDE GRHAGFLNRT MADLNVALDL TVLQKRKKYT YFQPKFIFYS VYLSEKIGYS 

       190        200        210        220        230        240 
RYINIYRHLE QNPQYCIHPI FKWFEQWCND EYRHGEFFAL LMRSQPEMLE GANRRWIRFF 

       250        260        270        280        290        300 
LLAVYATMYL NDARRANFYA ALGLNWRDYD QKVIRLCNDI ATQVYPETMN LDDPRFFGYM 

       310        320        330        340        350        360 
DKLVEYDRKL RELEGRKDPV ALAQSTRLKA AIALRLLAIY RLPTRKTTEA IRWKGLPGFP 

       370 
NYPGPNRPQR VAAAD

« Hide

References

[1]"Complete sequence of Chloroflexus aggregans DSM 9485."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MD-66 / DSM 9485.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001337 Genomic DNA. Translation: ACL24193.1.
RefSeqYP_002462629.1. NC_011831.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB8G814.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7266271.
GenomeReviewsGene locus Cagg_1285 in contig CP001337_GR.
KEGGcag:Cagg_1285.
PATRIC21405076. VBIChlAgg85409_1333.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284843.
OMAHGDFFDA.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8G814_CHLAD
AccessionPrimary (citable) accession number: B8G814
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info