B8G794 (B8G794_CHLAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase, degradative EMBL ACL24051.1
EC=1.1.1.88 EMBL ACL24051.1

Gene names

Ordered Locus Names:

Cagg_1141

Organism

Chloroflexus aggregans (strain MD-66 / DSM 9485) [Complete proteome] [HAMAP] EMBL ACL24051.1

Taxonomic identifier

326427 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length	440 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ACL24051.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8G794 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 130CC7966B39A7DA	FASTA	440	46,937
	10 20 30 40 50 60 MGTKNSRLQG FYQLNPFERL QMVKSFDGLV DEDLRALHGG QGGALTLERA DKMIENVVGT 70 80 90 100 110 120 YNLPLGIATN FRINGRDYLI PMVVEEPSIV AGASYAARMV RDGGGFETSS TEPLMIGQVQ 130 140 150 160 170 180 LVNIANPDQA REAILARKDE ILALANAQSR SLVALGGGAR DVEVRFFPTS PMGPMLVVHL 190 200 210 220 230 240 IVDCRDAMGA NAVNTMAEAV APLLADITGG KVYLRILSNL TDRRLARARC VVPAASLARD 250 260 270 280 290 300 GLSGEEVVEG ILWAYAFAAV DPYRAATHNK GIMNGIDPIL VATGNDWRAV EAGAHAYASR 310 320 330 340 350 360 NGRYTSLSHW ERDENGNLVG TLEMPLSVGI VGGATKVHPT AQAALKLLGV RSANELAEVC 370 380 390 400 410 420 VAAGLANNLA AMRALACEGI QQGHMSLHAR QIALAAGATG TLVDEVARRM VAERNIKPAR 430 440 AEEIIAELER RQHAGNPSHN

References

[1]

"Complete sequence of Chloroflexus aggregans DSM 9485." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MD-66 / DSM 9485.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001337 Genomic DNA. Translation: ACL24051.1.
RefSeq	YP_002462487.1. NC_011831.1.
3D structure databases
ProteinModelPortal	B8G794.
SMR	B8G794. Positions 5-427.
ModBase	Search...
Protein-protein interaction databases
STRING	B8G794.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7267889.
GenomeReviews	Gene locus Cagg_1141 in contig CP001337_GR.
KEGG	cag:Cagg_1141.
PATRIC	21404774. VBIChlAgg85409_1183.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG477902.
OMA	NNKGIMN.
ProtClustDB	CLSK972954.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
PANTHER	PTHR10572. HMG-CoA_red. 1 hit.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00066. HMG_COA_REDUCTASE_1. 1 hit. PS00318. HMG_COA_REDUCTASE_2. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8G794_CHLAD

Accession

Primary (citable) accession number: B8G794

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)