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B8G4H3

- PGK_CHLAD

UniProt

B8G4H3 - PGK_CHLAD

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Protein

Phosphoglycerate kinase

Gene
pgk, Cagg_0642
Organism
Chloroflexus aggregans (strain MD-66 / DSM 9485)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371Substrate By similarity
Binding sitei121 – 1211Substrate By similarity
Binding sitei154 – 1541Substrate By similarity
Binding sitei204 – 2041ATP By similarity
Binding sitei326 – 3261ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3584ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCAGG326427:GHS8-646-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Cagg_0642
OrganismiChloroflexus aggregans (strain MD-66 / DSM 9485)
Taxonomic identifieri326427 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
ProteomesiUP000002508: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Phosphoglycerate kinaseUniRule annotationPRO_1000192815Add
BLAST

Proteomic databases

PRIDEiB8G4H3.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi326427.Cagg_0642.

Structurei

3D structure databases

ProteinModelPortaliB8G4H3.
SMRiB8G4H3. Positions 1-398.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni21 – 233Substrate binding By similarity
Regioni60 – 634Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiFPVDYVT.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.

Sequencei

Sequence statusi: Complete.

B8G4H3-1 [UniParc]FASTAAdd to Basket

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MNKKTIRDVD WAGKRALVRV DFNVPLDEQG QITDDTRIRA ALPTIRYLLE    50
HGAKVILMSH LGRPKGKPNP KYSLRPVVER LFELLPEATE VKKTEAITGP 100
AAEAAVSMLK PGQVLVLENT RFDPREEAND PQMAAELAKL GDVFVNDAFG 150
TAHRANASTE GVAHYLPAVA GFLMEKELTY IGGALSNPQR PFVTVIGGAK 200
ISDKIGVIEN LLGKVDALLI GGGMANTFLL AKGLNLGDSL VEPESVPVAQ 250
QLMAKAEERG ARLLLPVDVV IADAFSAEAQ RQVVEVTAIP SGWRVLDIGP 300
KTIELYSAEI RSARTVIWNG PMGVFELEPF AAGTRAIAQA MAEASANGAI 350
TIVGGGDSVA AVEQAGLAEK MAHVSTGGGA SLELLEGRVL PGVAALQDAE 400
Length:400
Mass (Da):42,345
Last modified:March 3, 2009 - v1
Checksum:iC7D254B6D5D7DE52
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001337 Genomic DNA. Translation: ACL23579.1.
RefSeqiYP_002462015.1. NC_011831.1.

Genome annotation databases

EnsemblBacteriaiACL23579; ACL23579; Cagg_0642.
GeneIDi7266114.
KEGGicag:Cagg_0642.
PATRICi21403733. VBIChlAgg85409_0672.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001337 Genomic DNA. Translation: ACL23579.1 .
RefSeqi YP_002462015.1. NC_011831.1.

3D structure databases

ProteinModelPortali B8G4H3.
SMRi B8G4H3. Positions 1-398.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326427.Cagg_0642.

Proteomic databases

PRIDEi B8G4H3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL23579 ; ACL23579 ; Cagg_0642 .
GeneIDi 7266114.
KEGGi cag:Cagg_0642.
PATRICi 21403733. VBIChlAgg85409_0672.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi FPVDYVT.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci CAGG326427:GHS8-646-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Chloroflexus aggregans DSM 9485."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MD-66 / DSM 9485.

Entry informationi

Entry nameiPGK_CHLAD
AccessioniPrimary (citable) accession number: B8G4H3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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