B8G3Z5 (B8G3Z5_CHLAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pantothenate kinase HAMAP MF_00215
EC=2.7.1.33 HAMAP MF_00215

Alternative name(s):
Pantothenic acid kinase HAMAP MF_00215

Gene names

Name:	coaA HAMAP MF_00215
Ordered Locus Names:	Cagg_2526

Organism

Chloroflexus aggregans (strain MD-66 / DSM 9485) [Complete proteome] [HAMAP] EMBL ACL25397.1

Taxonomic identifier

326427 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Chloroflexus

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. HAMAP MF_00215
Subcellular location	Cytoplasm By similarity HAMAP MF_00215.
Sequence similarities	Belongs to the prokaryotic pantothenate kinase family. HAMAP MF_00215

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis HAMAP MF_00215
Cellular component	Cytoplasm HAMAP MF_00215
Ligand	ATP-binding HAMAP MF_00215 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00215 EMBL ACL25397.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP pantothenate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	97 – 104	8	ATP By similarity HAMAP MF_00215

Sequences

	Sequence		Length	Mass (Da)
	B8G3Z5 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 88833652B3F16A14	FASTA	318	36,743
	10 20 30 40 50 60 MIPKPELEQR LSPYLSFSRA EWSALRNGTP LPLSADELAS LVSLNDSVSI EDVADIYLPL 70 80 90 100 110 120 VRLLQLYYDN ATRLYQATST FFGSATGRVP YVIGIAGSVA VGKSSTARIL QALLSRSPYH 130 140 150 160 170 180 LKVNLITTDG FLYPNRVLQE RGIMHRKGFP ESYDRRRLLK FMADIKSGYG PVSAPVYSHL 190 200 210 220 230 240 IYDIVPDQFQ VVDHPDVLIV EGLNVLQRGM NTRREPQLYV SDFFDFAIYV DANERDLEQW 250 260 270 280 290 300 YIERFLRLRQ TAFRDPSSYF RRYADLSEIE AIATARRIWR EINYVNLKQN IEPTRWSADL 310 ILVKGPRHEL ERVYLRKL

References

[1]

"Complete sequence of Chloroflexus aggregans DSM 9485." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Bryant D.A., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MD-66 / DSM 9485.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001337 Genomic DNA. Translation: ACL25397.1.
RefSeq	YP_002463833.1. NC_011831.1.
3D structure databases
ProteinModelPortal	B8G3Z5.
SMR	B8G3Z5. Positions 8-317.
ModBase	Search...
Protein-protein interaction databases
STRING	B8G3Z5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7269372.
GenomeReviews	Gene locus Cagg_2526 in contig CP001337_GR.
KEGG	cag:Cagg_2526.
PATRIC	21407685. VBIChlAgg85409_2617.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG732538.
OMA	EVYLPLS.
ProtClustDB	PRK05439.
Family and domain databases
HAMAP	MF_00215. Pantothen_kinase_1. [Tree]
InterPro	IPR004566. PanK_bact. IPR006083. PRK/URK. [Graphical view]
KO	K00867.
PANTHER	PTHR10285:SF7. PanK_bact. 1 hit.
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PIRSF	PIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMs	TIGR00554. PanK_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8G3Z5_CHLAD

Accession

Primary (citable) accession number: B8G3Z5

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)