ID   B8G3G1_CHLAD            Unreviewed;       933 AA.
AC   B8G3G1;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE            Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN   Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN   OrderedLocusNames=Cagg_0399 {ECO:0000313|EMBL:ACL23344.1};
OS   Chloroflexus aggregans (strain MD-66 / DSM 9485).
OC   Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=326427 {ECO:0000313|EMBL:ACL23344.1, ECO:0000313|Proteomes:UP000002508};
RN   [1] {ECO:0000313|Proteomes:UP000002508}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MD-66 / DSM 9485 {ECO:0000313|Proteomes:UP000002508};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Bryant D.A., Richardson P.;
RT   "Complete sequence of Chloroflexus aggregans DSM 9485.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC       for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC       ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC         phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC         Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC         Rule:MF_00595};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00595};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR   EMBL; CP001337; ACL23344.1; -; Genomic_DNA.
DR   RefSeq; WP_012615710.1; NC_011831.1.
DR   AlphaFoldDB; B8G3G1; -.
DR   STRING; 326427.Cagg_0399; -.
DR   KEGG; cag:Cagg_0399; -.
DR   eggNOG; COG2352; Bacteria.
DR   HOGENOM; CLU_006557_2_0_0; -.
DR   OrthoDB; 9768133at2; -.
DR   Proteomes; UP000002508; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
PE   3: Inferred from homology;
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW   Rule:MF_00595};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW   Pyruvate {ECO:0000313|EMBL:ACL23344.1}.
FT   ACT_SITE        149
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT                   ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        595
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00595"
SQ   SEQUENCE   933 AA;  105609 MW;  5D6422E3D8FA5343 CRC64;
     MSGRTTAGEH DLLSANIRTL GDMLGRVITE QSGAATFELV ERVRLMAKEL RNGAPPAGTH
     VLQDLITGLS LPQLRNLVKA FTLYFGLVNL AEGVEQLRVL RSRDLRNAPA PRAESIADAI
     ELLKRHGVPA AAIQEWIDQA LIMPVFTAHP TESRRRTILI KLRRIFDTLI DLTFGERLVL
     PSDRQSALTR IERETVGLWQ TDDVRNRRPS VLDEVENGLF YFQTVLWDLI PEIYRETADA
     LATAYPDHRW RLPPFLRFGS WMGGDRDGNP FVTPEVTVET VRLMRSAMLR YLINGIDRLI
     TDLSQSVQQV PVDQAIFDRI AEYHELMPDA AATLNPHYRC EPYRQLCHFI QARLQNTLHY
     TLSHTPRWGA DPPPPRLPTI YYHSRELLAD LDLIDTSLRR HGGAIIADGL LRDLRTNVAV
     CRLHTATLDV RQHASRHTEA LTEILAGAGV VANYAALDEC ERVAVLSTEI RRPRPLTPIR
     LGHFSPATAE TVQTFRMLAA ISEQLDPEIF QTYIISTTSQ VSDLLAVLLF CRDAGLYQPG
     QYSRLDIVPL FETGEDLQRA PLILDELLQL PVYREHLALR DNLQEVMLGY SDSNKEGGFL
     AANWALYRAQ VELNTVTERH GVRLRFFHGR GGAVGRGGGP AGQAILAQPP GTLHGQIKVT
     NQGEVISDRY LDPRTAHRHL EQVVNAVLRA GFPGIARSPE PAWLEAMEQM AHTARTVYRR
     LVYEDPDFLT YFRNATPVAE LSRLRIGSRP VSRRKSDRIE DLRAIPWVFS WMQTRHTLPG
     WFGLGSALSE FVAADPHHLY VLRAMYRHWP FFTTLLDNAQ MIMLKADMSI ARSYAGLVPD
     QELAARIFQQ IEAEYRRTEH MICQITESQE LLAHQPVLQR AIRQRNPYID PLSYIQIELL
     RRIRNAPPED QDEIETVLLM SINGIAAGLK NTG
//