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B8FZ85 (B8FZ85_DESHD) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2621Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1331Substrate By similarity HAMAP-Rule MF_01201
Binding site3351Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
B8FZ85 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 672BE94E94BCF915

FASTA39443,802
        10         20         30         40         50         60 
MSDAWIDINL DAIANNYREV TQQLSPAARV MAVVKADAYG LGAVPVAQTL QKLGCPAFAV 

        70         80         90        100        110        120 
TTVEEGLILR QHGVEGIILV LGPVSAEQMA EALTGDLQLT LSDFHMLREW ETVAAGLGIE 

       130        140        150        160        170        180 
AKVHLKLETG MGRTGFFEKE WGELAAQLKK SPHITPVGVY THLARAAQRD RAYTRQQVES 

       190        200        210        220        230        240 
FQRGVNLLEE QGFAGLWKHV CNSAAFLDYP DWHYDFIRTG TLLIGHIPAP AFAGKLKLQD 

       250        260        270        280        290        300 
PWVAKARIVS LRRVPIGTFV GYQSIYRTKA ETQLAVIPVG YADGFGVQPH FVPQGVWDFI 

       310        320        330        340        350        360 
KIVIKNFLAL CRIYIGQESV ILQGHRVPVA GKIGMQLTVL DVGNLPCETG DEVILPLRRT 

       370        380        390 
QANPRLLRQY WSEKRLIAKR HIKEGFLQSY PEYP 

« Hide

References

[1]"Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction."
Kim S.H., Harzman C., Davis J.K., Hutcheson R., Broderick J.B., Marsh T.L., Tiedje J.M.
BMC Microbiol. 12:21-21(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DCB-2 / DSM 10664.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001336 Genomic DNA. Translation: ACL22837.1.
RefSeqYP_002461273.1. NC_011830.1.

3D structure databases

ProteinModelPortalB8FZ85.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272564.Dhaf_4842.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL22837; ACL22837; Dhaf_4842.
GeneID7261871.
KEGGdhd:Dhaf_4842.
PATRIC21667753. VBIDesHaf15223_5026.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAPVELWGQ.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycDHAF272564:GCV8-4928-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8FZ85_DESHD
AccessionPrimary (citable) accession number: B8FZ85
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)