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Protein

Adenine deaminase

Gene

ade

Organism
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciDHAF272564:GCV8-1737-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Dhaf_1712
OrganismiDesulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Taxonomic identifieri272564 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
Proteomesi
  • UP000007726 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 566566Adenine deaminasePRO_1000185086Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB8FPU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

B8FPU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDRNLKKLA PKSLGREKAQ LVLKNAQVIN VFSEEILVRD VAVEDGVIVG
60 70 80 90 100
VGQYQGREEV DLSGKYLCPG FIDAHLHLES TLVAPPELIH SALQWGTTTF
110 120 130 140 150
IIDPHEVVNV AGEEGLDYML EQTEGLAANV FLMLPSCVPA VPFEENGGVF
160 170 180 190 200
SAEKMEPYLA NPRVLGLGEV MDYVSVIEAE EGMVKKLRLF RERIKDGHAP
210 220 230 240 250
YLQDKQLAAY ALAGIKTDHE CIDYAYALEE VRNGMQVLIR EGSGARNLEA
260 270 280 290 300
IVRGIRDNSM DTGNFSFCTD DKHINDIQRE GHISYNIKKS IALGIPPLKA
310 320 330 340 350
IKMATINTAR CYNLTKLGAV APGYQADFVI LDSLEEVAVH AVYHKGKKVD
360 370 380 390 400
REKKIEIKPC PEQLRRTVHL PNLSADDLKL AVPDSPSSLI QMIEGQITTK
410 420 430 440 450
HVRDVLPAQD GCFVPNAQYN KVVVVERHKG TGHFAVAPVL GFNLRQGAIA
460 470 480 490 500
TSVSHDSHNV VAIGDNDESI LLALQELQRV QGGYTMIRGQ RVLATLPLPI
510 520 530 540 550
MGLISDAGYQ AVENTLNQMI GYAHEMGVPA HTHPFIALSF IALPVIPEIR
560
ITTRGLYDVV DQEFIR
Length:566
Mass (Da):62,342
Last modified:March 3, 2009 - v1
Checksum:iF74F4E78D3EAA2FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001336 Genomic DNA. Translation: ACL19758.1.
RefSeqiWP_015943614.1. NC_011830.1.

Genome annotation databases

EnsemblBacteriaiACL19758; ACL19758; Dhaf_1712.
KEGGidhd:Dhaf_1712.
PATRICi21661161. VBIDesHaf15223_1783.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001336 Genomic DNA. Translation: ACL19758.1.
RefSeqiWP_015943614.1. NC_011830.1.

3D structure databases

ProteinModelPortaliB8FPU4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL19758; ACL19758; Dhaf_1712.
KEGGidhd:Dhaf_1712.
PATRICi21661161. VBIDesHaf15223_1783.

Phylogenomic databases

HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciDHAF272564:GCV8-1737-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction."
    Kim S.H., Harzman C., Davis J.K., Hutcheson R., Broderick J.B., Marsh T.L., Tiedje J.M.
    BMC Microbiol. 12:21-21(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DCB-2 / DSM 10664.

Entry informationi

Entry nameiADEC_DESHD
AccessioniPrimary (citable) accession number: B8FPU4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: November 11, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.