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Protein
Submitted name:

Tryptophanyl-tRNA synthetase

Gene

Dhaf_3426

Organism
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. tryptophan-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationImported, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDHAF272564:GCV8-3500-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Tryptophanyl-tRNA synthetaseImported (EC:6.1.1.2Imported)
Gene namesi
Ordered Locus Names:Dhaf_3426Imported
OrganismiDesulfitobacterium hafniense (strain DCB-2 / DSM 10664)Imported
Taxonomic identifieri272564 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
ProteomesiUP000007726: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi272564.Dhaf_3426.

Structurei

3D structure databases

ProteinModelPortaliB8FPL2.
SMRiB8FPL2. Positions 3-325.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000059941.
KOiK01867.
OMAiWVRLQSE.
OrthoDBiEOG686NJQ.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8FPL2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKGRIFSGMR PTGSLHIGHL SVIQNWAALQ SEYQSYYGIV DQHALTTGYE
60 70 80 90 100
DGLDFGVLIR EIALDWLSVG IDPEQSAIFV QSHIKEHAEL HLLLSMITPL
110 120 130 140 150
SWLERVPTYK DQMQQLGKEG GKDISTYGFL GYPLLMAADI LVYKADTVPV
160 170 180 190 200
GEDQIPHVEL CREIARRFNH LYGPVFPEPK ALIGKVPLLP GVDGRKMSKS
210 220 230 240 250
YNNTISLTAS TAEIKERVQQ MVTDPARLRK DDPGHPEVCI VYKFHEVYTP
260 270 280 290 300
EVAEVEENCR GGKIGCVACK RHLAENLDKL LSPFRERRAL WEEPGKVERV
310 320
LEQGAEQARQ VTQETMKEVR HVMGLR
Length:326
Mass (Da):36,800
Last modified:March 3, 2009 - v1
Checksum:iC6E1548EB762E03A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001336 Genomic DNA. Translation: ACL21444.1.
RefSeqiWP_015944601.1. NC_011830.1.
YP_002459880.1. NC_011830.1.

Genome annotation databases

EnsemblBacteriaiACL21444; ACL21444; Dhaf_3426.
GeneIDi7260444.
KEGGidhd:Dhaf_3426.
PATRICi21664825. VBIDesHaf15223_3571.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001336 Genomic DNA. Translation: ACL21444.1.
RefSeqiWP_015944601.1. NC_011830.1.
YP_002459880.1. NC_011830.1.

3D structure databases

ProteinModelPortaliB8FPL2.
SMRiB8FPL2. Positions 3-325.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272564.Dhaf_3426.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL21444; ACL21444; Dhaf_3426.
GeneIDi7260444.
KEGGidhd:Dhaf_3426.
PATRICi21664825. VBIDesHaf15223_3571.

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000059941.
KOiK01867.
OMAiWVRLQSE.
OrthoDBiEOG686NJQ.

Enzyme and pathway databases

BioCyciDHAF272564:GCV8-3500-MONOMER.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction."
    Kim S.H., Harzman C., Davis J.K., Hutcheson R., Broderick J.B., Marsh T.L., Tiedje J.M.
    BMC Microbiol. 12:21-21(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DCB-2 / DSM 10664Imported.

Entry informationi

Entry nameiB8FPL2_DESHD
AccessioniPrimary (citable) accession number: B8FPL2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 4, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.