Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60 kDa chaperonin

Gene

groL

Organism
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Dhaf_1406
OrganismiDesulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Taxonomic identifieri272564 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesPeptococcaceaeDesulfitobacterium
Proteomesi
  • UP000007726 Componenti: Chromosome

Subcellular locationi

B8FNT7:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001470291 – 54460 kDa chaperoninAdd BLAST544

Proteomic databases

PRIDEiB8FNT7.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB8FNT7.
SMRiB8FNT7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

B8FNT7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKQIVFNEE ARRALERGVN ALAESVRVTL GPKGRNVVLD KKFGAPLITN
60 70 80 90 100
DGVTIAREIE LEDPFENMGA QLVKEVATKT NDVAGDGTTT ATVLAQAIIR
110 120 130 140 150
EGLKNVAAGA NPMGIKRGIE KAVESVVEDI KTNAKPIESK ESIAQVASIS
160 170 180 190 200
AGDDNIGVLI SDAMEKVGKD GVITVEEAKG MTTELKVVEG MQFDRGYLSA
210 220 230 240 250
YMITDTDKME AILNDPYILI TDKKIGAIAD ILPVLEKVVQ AGRQLLIIAE
260 270 280 290 300
DIEGEALATL ILNKLRGTFT CVAVKAPGFG DRRKAMLEDI AILTGGTVIT
310 320 330 340 350
EDLGLKLENT TIDMLGRARQ IRVTKEETTI VEGSGSQDDI KSRVEAIKKQ
360 370 380 390 400
IDETTSDFDR EKLQERLAKL AGGVAVIQVG AATEVEMKEK KLRIEDALAA
410 420 430 440 450
TRAAVEEGIV AGGGCALVDA AKALDSLKLT GDEKTGVAIV CRALEEPLRQ
460 470 480 490 500
IANNAGFEGS IVVEKVRNGG RGVGFNALTE AYEDMIAAGI VDPAKVTRSA
510 520 530 540
LQNAASIAAM LLTTECLVSD IPSKDNGAAA MAGMGGMGGM GGMM
Length:544
Mass (Da):57,382
Last modified:March 3, 2009 - v1
Checksum:i99AF662C482CEFAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001336 Genomic DNA. Translation: ACL19462.1.
RefSeqiWP_015943412.1. NC_011830.1.

Genome annotation databases

EnsemblBacteriaiACL19462; ACL19462; Dhaf_1406.
KEGGidhd:Dhaf_1406.

Similar proteinsi

Entry informationi

Entry nameiCH60_DESHD
AccessioniPrimary (citable) accession number: B8FNT7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: October 25, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families