B8FKD9 (SYGA_DESAA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	Dalk_0044

Organism

Desulfatibacillum alkenivorans (strain AK-01) [Complete proteome] [HAMAP]

Taxonomic identifier

439235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobacteraceae › Desulfatibacillum

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 288	288	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000197175

Sequences

	Sequence		Length	Mass (Da)
	B8FKD9 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 6ACC4F057DA1A026	FASTA	288	32,943
	10 20 30 40 50 60 MTFQDIILTL QKYWAEKGCV LVQPYDMEVG AGTFHPETLL RSLGPEPWKT AYVQPSRRPT 70 80 90 100 110 120 DGRYGENPNR LQHYYQFQVI IKPSPDDVQG LYLDSLKAIG IDPLAHDIRF VEDDWESPTL 130 140 150 160 170 180 GAAGLGWEVW LDGMEITQFT YFQLAGSIEL SPVTVELTYG LERIAMYLQE IDNVYELDWN 190 200 210 220 230 240 GVVKYGDLHH MNEVEQSTYN FEVANVDMLL GFFDSYEAEA KACLEKELVL PAYEYCLKCS 250 260 270 280 HTFNLLDARG AISVTERTGY IARIRNMARG CAEKYLEQRE SMGFPLAK

References

[1]

"Complete sequence of Desulfatibacillum alkenivorans AK-01." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Wawrik B., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AK-01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001322 Genomic DNA. Translation: ACL01754.1.
RefSeq	YP_002429222.1. NC_011768.1.
3D structure databases
ProteinModelPortal	B8FKD9.
SMR	B8FKD9. Positions 1-277.
ModBase	Search...
Protein-protein interaction databases
STRING	B8FKD9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7163951.
GenomeReviews	Gene locus Dalk_0044 in contig CP001322_GR.
KEGG	dal:Dalk_0044.
PATRIC	21646332. VBIDesAlk8144_0046.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285316.
OMA	CRRPTDG.
ProtClustDB	PRK09348.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_DESAA

Accession

Primary (citable) accession number: B8FKD9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program