Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Desulfatibacillum alkenivorans (strain AK-01)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei386 – 3861UniRule annotation
Active sitei514 – 5141UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciDALK439235:GHP2-1029-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Dalk_1023
OrganismiDesulfatibacillum alkenivorans (strain AK-01)
Taxonomic identifieri439235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfatibacillum
ProteomesiUP000000739: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Glucose-6-phosphate isomerasePRO_1000135525Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi439235.Dalk_1023.

Structurei

3D structure databases

ProteinModelPortaliB8FK51.
SMRiB8FK51. Positions 14-546.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8FK51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTNPVKTR AWLFLEKHYE DIKNRHMRDF FKEDPRRFDN FSLALDDILV
60 70 80 90 100
DFSKNRITTK TLELLLNLAH EAGLKEMINS MFSGEHINET ENRAVLHTAL
110 120 130 140 150
RRQGDEPVLA DGKDVMPDVR AVLEQMRVFS GRIITGEWKG FTGKAITDVV
160 170 180 190 200
NIGIGGSDLG PVMVTECLKP YAKPHMNVHF VSNVDGTHIA ETLKLLNPET
210 220 230 240 250
TLFMIASKTF TTQETMTNAY TARAWFLEKA GDKKHVARHF VALSTNKEAV
260 270 280 290 300
EEFGIDSQNM FEFWDWVGGR YSLWSAIGLS IACYVGFENF HELLKGAYAM
310 320 330 340 350
DVHFQKEPFE RNIPVILALI GIWYNNFFNA QTEAILPYDQ YMHRFPAYFQ
360 370 380 390 400
QGNMESNGKS VDRDGNPVTW QTGPIIWGEP GTNGQHAFYQ LIHQGTKMIP
410 420 430 440 450
ADFLAPAQSH NPIGEHHKIL LSNFFAQTEA LMNGKTAAEV QKELEAAGKL
460 470 480 490 500
PEEIAEILPH KVFDGNRPTN SILFKKLTPR TLGSLIAMYE HKIFVQGALW
510 520 530 540
NIYSFDQWGV ELGKQLAKKI LPELEDERPV NSHDASTNGL INAFKHMMG
Length:549
Mass (Da):62,306
Last modified:March 3, 2009 - v1
Checksum:i3262250364E3FF9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001322 Genomic DNA. Translation: ACL02726.1.
RefSeqiYP_002430194.1. NC_011768.1.

Genome annotation databases

EnsemblBacteriaiACL02726; ACL02726; Dalk_1023.
GeneIDi7164936.
KEGGidal:Dalk_1023.
PATRICi21648414. VBIDesAlk8144_1081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001322 Genomic DNA. Translation: ACL02726.1.
RefSeqiYP_002430194.1. NC_011768.1.

3D structure databases

ProteinModelPortaliB8FK51.
SMRiB8FK51. Positions 14-546.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi439235.Dalk_1023.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL02726; ACL02726; Dalk_1023.
GeneIDi7164936.
KEGGidal:Dalk_1023.
PATRICi21648414. VBIDesAlk8144_1081.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciDALK439235:GHP2-1029-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AK-01.

Entry informationi

Entry nameiG6PI_DESAA
AccessioniPrimary (citable) accession number: B8FK51
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: March 4, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.