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B8FJY6

- PUR5_DESAA

UniProt

B8FJY6 - PUR5_DESAA

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Desulfatibacillum alkenivorans (strain AK-01)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDALK439235:GHP2-715-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:Dalk_0709
OrganismiDesulfatibacillum alkenivorans (strain AK-01)
Taxonomic identifieri439235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfatibacillum
ProteomesiUP000000739: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 347347Phosphoribosylformylglycinamidine cyclo-ligasePRO_1000148277Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi439235.Dalk_0709.

Structurei

3D structure databases

ProteinModelPortaliB8FJY6.
SMRiB8FJY6. Positions 3-344.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiVIGKIEH.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

B8FJY6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAKSLSYADA GVDIDKANRL VDRIKTIVKS TPRQGVIGGI GGFGGLFSLN
60 70 80 90 100
TEQYERPVLV SSTDGVGTKL RVAIMMDKHD TIGIDLVAMS VNDILVQGAK
110 120 130 140 150
PLFFLDYLSM GKLNENTAAD IIEGVAEGCR QANCALIGGE TAEMPGMYED
160 170 180 190 200
GDYDLAGFAV GIADNFKIVD GSDVGQGNVL LGIASTGLHS NGYSLARKVF
210 220 230 240 250
FDHLGLKVDS YVEDLGMTVG EAMLEPTKIY AEIVRNLIRD IHVNGMAHIT
260 270 280 290 300
GGGIIDNLPR TIPQSCKAII REGSWEYPAI FPFMKKAGDI DEMEMMRTFN
310 320 330 340
NGIGLVAVIP EPQVQEALEL MQAMGEKAYV IGEIAARGEN DDRIEWK
Length:347
Mass (Da):37,443
Last modified:March 3, 2009 - v1
Checksum:iE4EB1C86002A896F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001322 Genomic DNA. Translation: ACL02414.1.
RefSeqiWP_012609853.1. NC_011768.1.
YP_002429882.1. NC_011768.1.

Genome annotation databases

EnsemblBacteriaiACL02414; ACL02414; Dalk_0709.
GeneIDi7164622.
KEGGidal:Dalk_0709.
PATRICi21647768. VBIDesAlk8144_0758.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001322 Genomic DNA. Translation: ACL02414.1 .
RefSeqi WP_012609853.1. NC_011768.1.
YP_002429882.1. NC_011768.1.

3D structure databases

ProteinModelPortali B8FJY6.
SMRi B8FJY6. Positions 3-344.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 439235.Dalk_0709.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL02414 ; ACL02414 ; Dalk_0709 .
GeneIDi 7164622.
KEGGi dal:Dalk_0709.
PATRICi 21647768. VBIDesAlk8144_0758.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi VIGKIEH.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci DALK439235:GHP2-715-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AK-01.

Entry informationi

Entry nameiPUR5_DESAA
AccessioniPrimary (citable) accession number: B8FJY6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3