B8FJY2 (B8FJY2_DESAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Choline dehydrogenase RuleBase RU003969
EC=1.1.99.1 RuleBase RU003969

Gene names

Ordered Locus Names:

Dalk_0705

Organism

Desulfatibacillum alkenivorans (strain AK-01) [Complete proteome] [HAMAP]

Taxonomic identifier

439235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobacteraceae › Desulfatibacillum

Protein attributes

Sequence length	554 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. RuleBase RU003969 SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867 RuleBase RU003968
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. RuleBase RU003969 SAAS SAAS007867
Sequence similarities	Belongs to the GMC oxidoreductase family. RuleBase RU003968

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533 RuleBase RU003968
Molecular function	Oxidoreductase SAAS SAAS007867 EMBL ACL02410.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8FJY2 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 3545306F359D493F	FASTA	554	62,027
	10 20 30 40 50 60 MARNYYDYII IGGGSAGSVL ANRLSVNPSN KVLVLEAGRP DYKMDFRIHM PAALTFPLAG 70 80 90 100 110 120 KTYNWWYESE PEPYMHNRRV YQPKGKVLGG SSCINGMIYI RGNALDYQKW AKEDGLENWD 130 140 150 160 170 180 YAHCLPYFQR FESRCMGADA YHGVGGPLYL TSPDLDNPLF TAFFRAVQEA GYPITEDVNG 190 200 210 220 230 240 FQQEGFSGFD RTCYRGRRWN AARAYVHPVK HRENLKVRTQ AAATRILFKG KKAIGVEYMK 250 260 270 280 290 300 GKTLNQAFGG EIVCCGGSIA SPQLLQVSGV GNGEELQKLG INVVHDLPGV GENLQDHLEV 310 320 330 340 350 360 YVQYGCKQPV SIAPALKWWR QPWIGFQWLF LRKGIGASNH FEAGGFIRSN DEVEYPNLQY 370 380 390 400 410 420 HFLPIAIRYD GSVAQEGHGY QVHVGPMNTD VRGTVKIKSA DPREYPAIQF NYLSTEQERK 430 440 450 460 470 480 NWVEAIKKTR EIMTQPAFDE LRGDELAPGP QCQTDEEILD FIAREGESAY HPSCTCKMGT 490 500 510 520 530 540 DDMAVVDPEL RVHGIENLRV VDASIMPYVT NGNIYAPTMM IAEKAADLIL GNTPAPPVEV 550 PYYTKGQNAA ASEE

References

[1]

"Complete sequence of Desulfatibacillum alkenivorans AK-01." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Wawrik B., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AK-01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001322 Genomic DNA. Translation: ACL02410.1.
RefSeq	YP_002429878.1. NC_011768.1.
3D structure databases
ProteinModelPortal	B8FJY2.
ModBase	Search...
Protein-protein interaction databases
STRING	B8FJY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7164618.
GenomeReviews	Gene locus Dalk_0705 in contig CP001322_GR.
KEGG	dal:Dalk_0705.
PATRIC	21647758. VBIDesAlk8144_0753.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734713.
OMA	RSTAPYY.
ProtClustDB	CLSK2546165.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8FJY2_DESAA

Accession

Primary (citable) accession number: B8FJY2

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)