B8FI72 (B8FI72_DESAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase 2 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023

Gene names

Name:	hisC2 HAMAP MF_01023
Ordered Locus Names:	Dalk_0935

Organism

Desulfatibacillum alkenivorans (strain AK-01) [Complete proteome] [HAMAP]

Taxonomic identifier

439235 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfobacterales › Desulfobacteraceae › Desulfatibacillum

Protein attributes

Sequence length	365 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ACL02639.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	225	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	B8FI72 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: F5AA39F7C0214450	FASTA	365	40,488
	10 20 30 40 50 60 MKPTAPEYFN IIPPYVPGKP MEELEREYGI KDSIKLASNE NPHGPSPKAM EAVKHALTNL 70 80 90 100 110 120 HRYPDGAAPE LMESIASKMG CQTSQIVLGN GSDEVIDMLA KVYLNAGDEA LMTEPSFMMY 130 140 150 160 170 180 SISALAQGAK AVKIPLTQDY RHDFDALAKA VTDKTKIIFL NSPQNPSGTV ITKEEFEPFL 190 200 210 220 230 240 EKVDPSILIV MDEAYIEFNR NSEAVIGLDY LNGDHTVVTL RTFSKLYGLA GLRIGFGVMP 250 260 270 280 290 300 EHASQMLNRI RPPFNINIPA QVAALAALSD SEFVEKTLET VHNGLDYLFD ALKEMDVVCY 310 320 330 340 350 360 PTQTNFFMID LKRDAKAVYE ALLYKGVIIR PLGSYGFDNH IRVTVGLPQE NERFVKALKD VMTGS

References

[1]

"Complete sequence of Desulfatibacillum alkenivorans AK-01." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Wawrik B., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AK-01.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001322 Genomic DNA. Translation: ACL02639.1.
RefSeq	YP_002430107.1. NC_011768.1.
3D structure databases
ProteinModelPortal	B8FI72.
ModBase	Search...
Protein-protein interaction databases
STRING	B8FI72.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7164848.
GenomeReviews	Gene locus Dalk_0935 in contig CP001322_GR.
KEGG	dal:Dalk_0935.
PATRIC	21648232. VBIDesAlk8144_0990.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646350.
OMA	YIELADI.
ProtClustDB	PRK02731.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8FI72_DESAA

Accession

Primary (citable) accession number: B8FI72

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)