Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B8FHH0

- DEF_DESAA

UniProt

B8FHH0 - DEF_DESAA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peptide deformylase

Gene

def

Organism
Desulfatibacillum alkenivorans (strain AK-01)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.UniRule annotation

Catalytic activityi

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide.UniRule annotation

Cofactori

Binds 1 Fe2+ ion.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi96 – 961IronUniRule annotation
Metal bindingi138 – 1381IronUniRule annotation
Active sitei139 – 1391UniRule annotation
Metal bindingi142 – 1421IronUniRule annotation

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. peptide deformylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Enzyme and pathway databases

BioCyciDALK439235:GHP2-558-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide deformylaseUniRule annotation (EC:3.5.1.88UniRule annotation)
Short name:
PDFUniRule annotation
Alternative name(s):
Polypeptide deformylaseUniRule annotation
Gene namesi
Name:defUniRule annotation
Ordered Locus Names:Dalk_0552
OrganismiDesulfatibacillum alkenivorans (strain AK-01)
Taxonomic identifieri439235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfatibacillum
ProteomesiUP000000739: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172Peptide deformylasePRO_1000200723Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi439235.Dalk_0552.

Structurei

3D structure databases

ProteinModelPortaliB8FHH0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polypeptide deformylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0242.
HOGENOMiHOG000243509.
KOiK01462.
OMAiDMYDTMD.
OrthoDBiEOG664CMF.

Family and domain databases

Gene3Di3.90.45.10. 1 hit.
HAMAPiMF_00163. Pep_deformylase.
InterProiIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
PANTHERiPTHR10458. PTHR10458. 1 hit.
PfamiPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFiPIRSF004749. Pep_def. 1 hit.
PRINTSiPR01576. PDEFORMYLASE.
SUPFAMiSSF56420. SSF56420. 1 hit.
TIGRFAMsiTIGR00079. pept_deformyl. 1 hit.

Sequencei

Sequence statusi: Complete.

B8FHH0 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALLDIVTYP APILGKPCKL IEDIDEDLVC LVEDMTETLY DAPGLGLAAV
60 70 80 90 100
QVGVDKAMLV YDVAEDENSE STGLKVLINP KIVHTEGKVT SENEGCLSVP
110 120 130 140 150
EFRADVPRFA CVTVEGVDHE GKPVKIDAEG LLAIVLQHEI DHLEGKLFID
160 170
RISSLKRSMY KRRVAKALKA EG
Length:172
Mass (Da):18,772
Last modified:March 3, 2009 - v1
Checksum:i288F69B406164E88
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001322 Genomic DNA. Translation: ACL02258.1.
RefSeqiYP_002429726.1. NC_011768.1.

Genome annotation databases

EnsemblBacteriaiACL02258; ACL02258; Dalk_0552.
GeneIDi7164465.
KEGGidal:Dalk_0552.
PATRICi21647438. VBIDesAlk8144_0593.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001322 Genomic DNA. Translation: ACL02258.1 .
RefSeqi YP_002429726.1. NC_011768.1.

3D structure databases

ProteinModelPortali B8FHH0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 439235.Dalk_0552.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL02258 ; ACL02258 ; Dalk_0552 .
GeneIDi 7164465.
KEGGi dal:Dalk_0552.
PATRICi 21647438. VBIDesAlk8144_0593.

Phylogenomic databases

eggNOGi COG0242.
HOGENOMi HOG000243509.
KOi K01462.
OMAi DMYDTMD.
OrthoDBi EOG664CMF.

Enzyme and pathway databases

BioCyci DALK439235:GHP2-558-MONOMER.

Family and domain databases

Gene3Di 3.90.45.10. 1 hit.
HAMAPi MF_00163. Pep_deformylase.
InterProi IPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view ]
PANTHERi PTHR10458. PTHR10458. 1 hit.
Pfami PF01327. Pep_deformylase. 1 hit.
[Graphical view ]
PIRSFi PIRSF004749. Pep_def. 1 hit.
PRINTSi PR01576. PDEFORMYLASE.
SUPFAMi SSF56420. SSF56420. 1 hit.
TIGRFAMsi TIGR00079. pept_deformyl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AK-01.

Entry informationi

Entry nameiDEF_DESAA
AccessioniPrimary (citable) accession number: B8FHH0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3