Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B8FCY5

- IF2_DESAA

UniProt

B8FCY5 - IF2_DESAA

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Desulfatibacillum alkenivorans (strain AK-01)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi548 – 5558GTPUniRule annotation
    Nucleotide bindingi594 – 5985GTPUniRule annotation
    Nucleotide bindingi648 – 6514GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: UniProtKB-HAMAP
    2. GTP binding Source: UniProtKB-KW
    3. translation initiation factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. small GTPase mediated signal transduction Source: InterPro

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDALK439235:GHP2-4801-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-2UniRule annotation
    Gene namesi
    Name:infBUniRule annotation
    Ordered Locus Names:Dalk_4738
    OrganismiDesulfatibacillum alkenivorans (strain AK-01)
    Taxonomic identifieri439235 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfatibacillum
    ProteomesiUP000000739: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10401040Translation initiation factor IF-2PRO_1000190631Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi439235.Dalk_4738.

    Structurei

    3D structure databases

    ProteinModelPortaliB8FCY5.
    SMRiB8FCY5. Positions 940-1035.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini539 – 706168tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni548 – 5558G1By similarity
    Regioni573 – 5775G2By similarity
    Regioni594 – 5974G3By similarity
    Regioni648 – 6514G4By similarity
    Regioni684 – 6863G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0532.
    HOGENOMiHOG000076906.
    KOiK02519.
    OMAiFECFEME.
    OrthoDBiEOG67HJSV.

    Family and domain databases

    Gene3Di3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00100_B. IF_2_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view]
    PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SUPFAMiSSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8FCY5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKLRVHELA RELNMTNKVL LDKLQAMDLP TPVRSHMSSL DDDVVALVKA     50
    SLVRPKAKSV VEKRIGTTVI RRRKKVVKPA EGGPEETAKP EEGAEEGVQE 100
    MDAAQESVSA PEAEKAPEPV AEKAPEPQKA APAAEEPKAE EGAPAPEKAA 150
    PVQAKEEPEE APQAEAKPAP PKKVDVTPPG DKAKIIAKPE PPQPAEPEPP 200
    KEEPAPVELP EEKQAVSAKA ADTPAEPQEE PEAKPEIKAE AKAEEGAPEK 250
    PAEEPKAKEE QKAAPEDSKE EPKAEEPAQP AEDEKAEEKA KAPEEKEPAK 300
    SQEPQAAKEP SKEAPKPKGK KKKKKETAAK IISLPTRPVE PVVPPASRQK 350
    PAPQSPAGPG GPGGPGVPPQ PRAPQDLGGD PAAKKEKRKK KGRRDGGTTE 400
    ETDSKFFKKK ISFRKKAVVE GADLYDKTPG KLRKGKKGGK AQPVRQQKTQ 450
    TTTPKAIKRR IKIDEAIAVA DLAKRLGIKA AELIKNLMGM GIMATVNQML 500
    DYDTAVLLAA EFGYEVEKAN FEEETVLKAE EDAPETLSNR PPVVTIMGHV 550
    DHGKTSLLDA IRESNVTGGE AGGITQHIGA YLVDSPRGRI AFLDTPGHEA 600
    FTAMRARGAQ VTDIVILVVA ADDGVMPQTV EAVNHSKAAG VPIIVAVNKM 650
    DKEGADPDRV MRELSDHGLV PEDWGGDTIF VQVSAKQRQG LDDLLEMVLL 700
    QAEVLELQAN PDKLARGHVV EAKVDPGRGP VATVLIQEGT LHAGDVVVCG 750
    IHYGKVRAMY NEKRQPLDAA GPACPAEILG LSGVPMAGDE IIAVDDEKVA 800
    KQVSSHRAQK QRATELAKSS KLSLDNLFDQ MQAGNVKDLN LIIKADVQGS 850
    IEALRESLEK LSGDEVKIHV VHAATGTVLE SDVALAAVSN AIIVAFNVRP 900
    SPKVSDMAAE EHVDIRFYDI IYNAINEIKD AIVGLMESTY KEHVSGRAEV 950
    RDTFTIPKVG TIAGCYVTDG KVERHNQVRL LRDGVVIFDG KLSSLRRFKD 1000
    DVKEVATGYE CGMGIENFND IKIGDVLELY YLEEIKPVLK 1040
    Length:1,040
    Mass (Da):111,922
    Last modified:March 3, 2009 - v1
    Checksum:iB612112D07102DB3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001322 Genomic DNA. Translation: ACL06416.1.
    RefSeqiWP_015949455.1. NC_011768.1.
    YP_002433884.1. NC_011768.1.

    Genome annotation databases

    EnsemblBacteriaiACL06416; ACL06416; Dalk_4738.
    GeneIDi7168708.
    KEGGidal:Dalk_4738.
    PATRICi21656382. VBIDesAlk8144_5012.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001322 Genomic DNA. Translation: ACL06416.1 .
    RefSeqi WP_015949455.1. NC_011768.1.
    YP_002433884.1. NC_011768.1.

    3D structure databases

    ProteinModelPortali B8FCY5.
    SMRi B8FCY5. Positions 940-1035.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 439235.Dalk_4738.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL06416 ; ACL06416 ; Dalk_4738 .
    GeneIDi 7168708.
    KEGGi dal:Dalk_4738.
    PATRICi 21656382. VBIDesAlk8144_5012.

    Phylogenomic databases

    eggNOGi COG0532.
    HOGENOMi HOG000076906.
    KOi K02519.
    OMAi FECFEME.
    OrthoDBi EOG67HJSV.

    Enzyme and pathway databases

    BioCyci DALK439235:GHP2-4801-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10050. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00100_B. IF_2_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR006847. IF2_N.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR001806. Small_GTPase.
    IPR000178. TF_IF2_bacterial-like.
    IPR015760. TIF_IF2.
    IPR023115. TIF_IF2_dom3.
    IPR009000. Transl_B-barrel.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    [Graphical view ]
    PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 2 hits.
    PF11987. IF-2. 1 hit.
    PF04760. IF2_N. 2 hits.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SUPFAMi SSF50447. SSF50447. 2 hits.
    SSF52156. SSF52156. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00487. IF-2. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51722. G_TR_2. 1 hit.
    PS01176. IF2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AK-01.

    Entry informationi

    Entry nameiIF2_DESAA
    AccessioniPrimary (citable) accession number: B8FCY5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3