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B8FCY5

- IF2_DESAA

UniProt

B8FCY5 - IF2_DESAA

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Protein

Translation initiation factor IF-2

Gene
infB, Dalk_4738
Organism
Desulfatibacillum alkenivorans (strain AK-01)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi548 – 5558GTP By similarity
Nucleotide bindingi594 – 5985GTP By similarity
Nucleotide bindingi648 – 6514GTP By similarity

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDALK439235:GHP2-4801-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2
Gene namesi
Name:infB
Ordered Locus Names:Dalk_4738
OrganismiDesulfatibacillum alkenivorans (strain AK-01)
Taxonomic identifieri439235 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfobacteralesDesulfobacteraceaeDesulfatibacillum
ProteomesiUP000000739: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10401040Translation initiation factor IF-2UniRule annotationPRO_1000190631Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi439235.Dalk_4738.

Structurei

3D structure databases

ProteinModelPortaliB8FCY5.
SMRiB8FCY5. Positions 940-1035.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini539 – 706168tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni548 – 5558G1 By similarity
Regioni573 – 5775G2 By similarity
Regioni594 – 5974G3 By similarity
Regioni648 – 6514G4 By similarity
Regioni684 – 6863G5 By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076906.
KOiK02519.
OMAiFECFEME.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
PRINTSiPR00449. RASTRNSFRMNG.
SUPFAMiSSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8FCY5-1 [UniParc]FASTAAdd to Basket

« Hide

MAKLRVHELA RELNMTNKVL LDKLQAMDLP TPVRSHMSSL DDDVVALVKA     50
SLVRPKAKSV VEKRIGTTVI RRRKKVVKPA EGGPEETAKP EEGAEEGVQE 100
MDAAQESVSA PEAEKAPEPV AEKAPEPQKA APAAEEPKAE EGAPAPEKAA 150
PVQAKEEPEE APQAEAKPAP PKKVDVTPPG DKAKIIAKPE PPQPAEPEPP 200
KEEPAPVELP EEKQAVSAKA ADTPAEPQEE PEAKPEIKAE AKAEEGAPEK 250
PAEEPKAKEE QKAAPEDSKE EPKAEEPAQP AEDEKAEEKA KAPEEKEPAK 300
SQEPQAAKEP SKEAPKPKGK KKKKKETAAK IISLPTRPVE PVVPPASRQK 350
PAPQSPAGPG GPGGPGVPPQ PRAPQDLGGD PAAKKEKRKK KGRRDGGTTE 400
ETDSKFFKKK ISFRKKAVVE GADLYDKTPG KLRKGKKGGK AQPVRQQKTQ 450
TTTPKAIKRR IKIDEAIAVA DLAKRLGIKA AELIKNLMGM GIMATVNQML 500
DYDTAVLLAA EFGYEVEKAN FEEETVLKAE EDAPETLSNR PPVVTIMGHV 550
DHGKTSLLDA IRESNVTGGE AGGITQHIGA YLVDSPRGRI AFLDTPGHEA 600
FTAMRARGAQ VTDIVILVVA ADDGVMPQTV EAVNHSKAAG VPIIVAVNKM 650
DKEGADPDRV MRELSDHGLV PEDWGGDTIF VQVSAKQRQG LDDLLEMVLL 700
QAEVLELQAN PDKLARGHVV EAKVDPGRGP VATVLIQEGT LHAGDVVVCG 750
IHYGKVRAMY NEKRQPLDAA GPACPAEILG LSGVPMAGDE IIAVDDEKVA 800
KQVSSHRAQK QRATELAKSS KLSLDNLFDQ MQAGNVKDLN LIIKADVQGS 850
IEALRESLEK LSGDEVKIHV VHAATGTVLE SDVALAAVSN AIIVAFNVRP 900
SPKVSDMAAE EHVDIRFYDI IYNAINEIKD AIVGLMESTY KEHVSGRAEV 950
RDTFTIPKVG TIAGCYVTDG KVERHNQVRL LRDGVVIFDG KLSSLRRFKD 1000
DVKEVATGYE CGMGIENFND IKIGDVLELY YLEEIKPVLK 1040
Length:1,040
Mass (Da):111,922
Last modified:March 3, 2009 - v1
Checksum:iB612112D07102DB3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001322 Genomic DNA. Translation: ACL06416.1.
RefSeqiWP_015949455.1. NC_011768.1.
YP_002433884.1. NC_011768.1.

Genome annotation databases

EnsemblBacteriaiACL06416; ACL06416; Dalk_4738.
GeneIDi7168708.
KEGGidal:Dalk_4738.
PATRICi21656382. VBIDesAlk8144_5012.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001322 Genomic DNA. Translation: ACL06416.1 .
RefSeqi WP_015949455.1. NC_011768.1.
YP_002433884.1. NC_011768.1.

3D structure databases

ProteinModelPortali B8FCY5.
SMRi B8FCY5. Positions 940-1035.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 439235.Dalk_4738.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL06416 ; ACL06416 ; Dalk_4738 .
GeneIDi 7168708.
KEGGi dal:Dalk_4738.
PATRICi 21656382. VBIDesAlk8144_5012.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076906.
KOi K02519.
OMAi FECFEME.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci DALK439235:GHP2-4801-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
PRINTSi PR00449. RASTRNSFRMNG.
SUPFAMi SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AK-01.

Entry informationi

Entry nameiIF2_DESAA
AccessioniPrimary (citable) accession number: B8FCY5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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