Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B8F8Q3

- B8F8Q3_HAEPS

UniProt

B8F8Q3 - B8F8Q3_HAEPS

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Haemophilus parasuis serovar 5 (strain SH0165)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciHPAR557723:GH24-2276-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:HAPS_2276Imported
    OrganismiHaemophilus parasuis serovar 5 (strain SH0165)Imported
    Taxonomic identifieri557723 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
    ProteomesiUP000006743: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi557723.HAPS_2276.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0538.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8F8Q3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLSQLTTPKG QAIQLNHDGS LSVPNYPIIP FIEGDGIGVD VTPAMRFVID    50
    AAVEKAYQGQ RKIDWLEIYA GEKANRLYGE NTWLPEETLA SIKQYHIAIK 100
    GPLMTPVGKG IRSLNVAMRQ ELDLYNCLRP IRYYQGTPSP VKYPELVDMV 150
    IFRENSEDIY AGVEWAAGSY EAEKVIAFLR QEMGVKKIRF TEECGIGIKP 200
    VSKEGTQRLV RAALQYAIDN DRKSLTLVHK GNIMKFTEGA FKEWGYQVAK 250
    DFGAEPIDNG SWHRLKNPNT GREIIIKDCI ADAFLQEILL HPSDYDVIAT 300
    LNLNGDYISD ALAAQVGGIG IAPGANIGEE AAIFEATHGT APKIAGQNKA 350
    NPGSIILSGE MMLRHLGWTE AADLVVNAVS KTISNKTVTF DFAETLEGAT 400
    LRTTSEFAQD IVANM 415
    Length:415
    Mass (Da):45,638
    Last modified:March 3, 2009 - v1
    Checksum:i313AF994EADC0040
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001321 Genomic DNA. Translation: ACL33705.1.
    RefSeqiWP_015940152.1. NC_011852.1.
    YP_002476653.1. NC_011852.1.

    Genome annotation databases

    EnsemblBacteriaiACL33705; ACL33705; HAPS_2276.
    GeneIDi7277242.
    KEGGihap:HAPS_2276.
    PATRICi20196906. VBIHaePar127548_2247.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001321 Genomic DNA. Translation: ACL33705.1 .
    RefSeqi WP_015940152.1. NC_011852.1.
    YP_002476653.1. NC_011852.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 557723.HAPS_2276.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL33705 ; ACL33705 ; HAPS_2276 .
    GeneIDi 7277242.
    KEGGi hap:HAPS_2276.
    PATRICi 20196906. VBIHaePar127548_2247.

    Phylogenomic databases

    eggNOGi COG0538.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci HPAR557723:GH24-2276-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Haemophilus parasuis SH0165."
      Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R., Jin M., Jin Q., Chen H.
      J. Bacteriol. 191:1359-1360(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SH0165Imported.

    Entry informationi

    Entry nameiB8F8Q3_HAEPS
    AccessioniPrimary (citable) accession number: B8F8Q3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3