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Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Haemophilus parasuis serovar 5 (strain SH0165) (Glaesserella parasuis)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

Cofactori

Mg2+UniRule annotation, Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processGlyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation
LigandManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciHPAR557723:G1GUF-2250-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Name:icdImported
Ordered Locus Names:HAPS_2276Imported
OrganismiHaemophilus parasuis serovar 5 (strain SH0165) (Glaesserella parasuis)Imported
Taxonomic identifieri557723 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeGlaesserella
Proteomesi
  • UP000006743 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi557723.HAPS_2276

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 411Iso_dhInterPro annotationAdd BLAST384

Phylogenomic databases

eggNOGiENOG4108HMX Bacteria
COG0538 LUCA
HOGENOMiHOG000021113
KOiK00031
OMAiFQQIQTR

Family and domain databases

InterProiView protein in InterPro
IPR019818 IsoCit/isopropylmalate_DH_CS
IPR004439 Isocitrate_DH_NADP_dimer_prok
IPR024084 IsoPropMal-DH-like_dom
PANTHERiPTHR43504 PTHR43504, 1 hit
PfamiView protein in Pfam
PF00180 Iso_dh, 1 hit
SMARTiView protein in SMART
SM01329 Iso_dh, 1 hit
TIGRFAMsiTIGR00183 prok_nadp_idh, 1 hit
PROSITEiView protein in PROSITE
PS00470 IDH_IMDH, 1 hit

Sequencei

Sequence statusi: Complete.

B8F8Q3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSQLTTPKG QAIQLNHDGS LSVPNYPIIP FIEGDGIGVD VTPAMRFVID
60 70 80 90 100
AAVEKAYQGQ RKIDWLEIYA GEKANRLYGE NTWLPEETLA SIKQYHIAIK
110 120 130 140 150
GPLMTPVGKG IRSLNVAMRQ ELDLYNCLRP IRYYQGTPSP VKYPELVDMV
160 170 180 190 200
IFRENSEDIY AGVEWAAGSY EAEKVIAFLR QEMGVKKIRF TEECGIGIKP
210 220 230 240 250
VSKEGTQRLV RAALQYAIDN DRKSLTLVHK GNIMKFTEGA FKEWGYQVAK
260 270 280 290 300
DFGAEPIDNG SWHRLKNPNT GREIIIKDCI ADAFLQEILL HPSDYDVIAT
310 320 330 340 350
LNLNGDYISD ALAAQVGGIG IAPGANIGEE AAIFEATHGT APKIAGQNKA
360 370 380 390 400
NPGSIILSGE MMLRHLGWTE AADLVVNAVS KTISNKTVTF DFAETLEGAT
410
LRTTSEFAQD IVANM
Length:415
Mass (Da):45,638
Last modified:March 3, 2009 - v1
Checksum:i313AF994EADC0040
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001321 Genomic DNA Translation: ACL33705.1
RefSeqiWP_015940152.1, NC_011852.1

Genome annotation databases

EnsemblBacteriaiACL33705; ACL33705; HAPS_2276
GeneIDi7277242
KEGGihap:HAPS_2276
PATRICifig|557723.8.peg.2247

Similar proteinsi

Entry informationi

Entry nameiB8F8Q3_HAEPS
AccessioniPrimary (citable) accession number: B8F8Q3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health