Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

B8F8Q3 (B8F8Q3_HAEPS) Unreviewed, UniProtKB/TrEMBL

Last modified November 13, 2013. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Name:icd EMBL ACL33705.1
Ordered Locus Names:HAPS_2276 EMBL ACL33705.1
OrganismHaemophilus parasuis serovar 5 (strain SH0165) [Complete proteome] [HAMAP] EMBL ACL33705.1
Taxonomic identifier557723 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family.

Sequences

Sequence LengthMass (Da)Tools
B8F8Q3 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 313AF994EADC0040

FASTA41545,638
        10         20         30         40         50         60 
MLSQLTTPKG QAIQLNHDGS LSVPNYPIIP FIEGDGIGVD VTPAMRFVID AAVEKAYQGQ 

        70         80         90        100        110        120 
RKIDWLEIYA GEKANRLYGE NTWLPEETLA SIKQYHIAIK GPLMTPVGKG IRSLNVAMRQ 

       130        140        150        160        170        180 
ELDLYNCLRP IRYYQGTPSP VKYPELVDMV IFRENSEDIY AGVEWAAGSY EAEKVIAFLR 

       190        200        210        220        230        240 
QEMGVKKIRF TEECGIGIKP VSKEGTQRLV RAALQYAIDN DRKSLTLVHK GNIMKFTEGA 

       250        260        270        280        290        300 
FKEWGYQVAK DFGAEPIDNG SWHRLKNPNT GREIIIKDCI ADAFLQEILL HPSDYDVIAT 

       310        320        330        340        350        360 
LNLNGDYISD ALAAQVGGIG IAPGANIGEE AAIFEATHGT APKIAGQNKA NPGSIILSGE 

       370        380        390        400        410 
MMLRHLGWTE AADLVVNAVS KTISNKTVTF DFAETLEGAT LRTTSEFAQD IVANM 

« Hide

References

[1]"Complete genome sequence of Haemophilus parasuis SH0165."
Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R., Jin M., Jin Q., Chen H.
J. Bacteriol. 191:1359-1360(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SH0165 EMBL ACL33705.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001321 Genomic DNA. Translation: ACL33705.1.
RefSeqYP_002476653.1. NC_011852.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING557723.HAPS_2276.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL33705; ACL33705; HAPS_2276.
GeneID7277242.
KEGGhap:HAPS_2276.
PATRIC20196906. VBIHaePar127548_2247.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
OrthoDBEOG6SNDTP.
ProtClustDBCLSK236871.

Enzyme and pathway databases

BioCycHPAR557723:GH24-2276-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8F8Q3_HAEPS
AccessionPrimary (citable) accession number: B8F8Q3
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 13, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)