B8F711 (SYGB_HAEPS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase beta subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase beta subunit
Short name=GlyRS

Gene names

Name:	glyS
Ordered Locus Names:	HAPS_1559

Organism

Haemophilus parasuis serovar 5 (strain SH0165) [Complete proteome] [HAMAP]

Taxonomic identifier

557723 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus parasuis

Protein attributes

Sequence length	689 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00255
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: InterPro glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 689	689	Glycine--tRNA ligase beta subunit HAMAP-Rule MF_00255		PRO_1000197202

Sequences

	Sequence		Length	Mass (Da)
	B8F711 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 8ABB781988A62A17	FASTA	689	76,027
	10 20 30 40 50 60 MTTQNFLAEI GTEELPPKAL KKLATAFAEN VEAELNQAGL SFDKVEWFAA PRRLAVKVLG 70 80 90 100 110 120 LATAQPSKEV EKRGPAVSAA FDAEGKPTKA AEGWAKGCGI TVEQAERIAT DKGEWLVHRA 130 140 150 160 170 180 VIEGQPTKNL LVGIISQALA KLPIPKTMRW GDKTEQFVRP VHTVTLLLGD ELIEGEILGV 190 200 210 220 230 240 ASGTTVRGHR FLGEREFQIS HADQYPALLK EKGSVVADFN ERKALILAKA QEKATALGGV 250 260 270 280 290 300 ADIEEDLLDE VTSLVEYPNV LAAKFEERFL AVPAEALVYT MKGDQKYFPI YDKDGKLLPH 310 320 330 340 350 360 FIFVSNINPE DPSKIIEGNE KVVRPRLTDA EFFFKTDLKQ RLEDQLPRLE TVLFQQQLGT 370 380 390 400 410 420 LRDKTARIEQ LAGEIAKQIG ADETKAKRAG LLSKCDLMTN MVFEFTDTQG VMGMHYARHD 430 440 450 460 470 480 GEDEEVAVAL NEQYMPRFAG DELPKSLVAS SVALADKFDT LTGIFGIGQA PKGSADPFAL 490 500 510 520 530 540 RRAALGALRI IVEKNLPLDL SDLVATSAKL FGDKLTNSNV VEEVVDFMLG RFRAWYQDEG 550 560 570 580 590 600 IAVDVIQAVL ARRPTRPADF DARVRAVSHF RTLDSAEALA AANKRVSNIL AKVEGKISSE 610 620 630 640 650 660 IDRTLLVEAE EKALAEQVIT LQAELVPLFE KGEYQTALDR LAGLREVVDN FFDKVMVNAE 670 680 DPKLRQNRQA ILNNLRNLFL QVADISLLQ

References

[1]	"Complete genome sequence of Haemophilus parasuis SH0165." Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R., Jin M., Jin Q., Chen H. J. Bacteriol. 191:1359-1360(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SH0165.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001321 Genomic DNA. Translation: ACL33113.1.
RefSeq	YP_002476061.1. NC_011852.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	557723.HAPS_1559.
Proteomic databases
PRIDE	B8F711.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL33113; ACL33113; HAPS_1559.
GeneID	7277007.
KEGG	hap:HAPS_1559.
PATRIC	20195415. VBIHaePar127548_1531.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0751.
HOGENOM	HOG000264303.
KO	K01879.
OMA	GMHYARL.
ProtClustDB	PRK01233.
Enzyme and pathway databases
BioCyc	HPAR557723:GH24-1559-MONOMER.
Family and domain databases
HAMAP	MF_00255. Gly_tRNA_synth_beta.
InterPro	IPR008909. DALR_anticod-bd. IPR015944. Gly-tRNA-synth_bsu. IPR006194. Gly-tRNA-synth_heterodimer. [Graphical view]
Pfam	PF05746. DALR_1. 1 hit. PF02092. tRNA_synt_2f. 1 hit. [Graphical view]
PRINTS	PR01045. TRNASYNTHGB.
SMART	SM00836. DALR_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00211. glyS. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGB_HAEPS

Accession

Primary (citable) accession number: B8F711

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program