B8F6I1 (B8F6I1_HAEPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA mismatch repair protein mutL HAMAP MF_00149

Gene names

Name:	mutL HAMAP MF_00149 EMBL ACL32933.1
Ordered Locus Names:	HAPS_1353

Organism

Haemophilus parasuis serovar 5 (strain SH0165) [Complete proteome] [HAMAP]

Taxonomic identifier

557723 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus

Protein attributes

Sequence length	589 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex By similarity. HAMAP MF_00149 SAAS SAAS020667
Sequence similarities	Belongs to the DNA mismatch repair mutL/hexB family. HAMAP MF_00149

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_00149 SAAS SAAS020667
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mismatch repair Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro mismatched DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8F6I1 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: B7E79C53381251A1	FASTA	589	66,361
	10 20 30 40 50 60 MERPASVVKE LVENSLDAGA TQIQIDIEKG GSQLIRIRDN GCGIGKQDLA LALARHATSK 70 80 90 100 110 120 IATLEDLESI LSLGFRGEAL ASISSVSRLT LTSRPEYQAE AWQAYAQGRE MEVEIKPASH 130 140 150 160 170 180 PVGTTIEVAN LFFNTPARRK FLRTDKTEFA HIDEVVRRIA LAKPNVTFTL THNEKKVRYY 190 200 210 220 230 240 KAVATQQLEQ QQKRVATICG DEFIQQSVHI DWQHDDLHIY GWVGSPSLAR VQNDLCYSYV 250 260 270 280 290 300 NGRMMRDKTI NHAIRQAYGE RLPKDHYPAF VLFLDLDPSH VDVNVHPAKH EVRFHQSRLV 310 320 330 340 350 360 HDFIYQGVLN ALEDQHHLPL TTNVSEALPN YIADTNRVAS GQNIFAHSYR EPRSTSSTHA 370 380 390 400 410 420 ERPNYSNTRS SGVSKNEQKW YGELLSTSPM QDYKRSEPVQ DLPKTAKITP LVEPIAEPVT 430 440 450 460 470 480 PYAQALAVVK QKALLIKQGE TFYLLSLEKL AQLKLQAELA KRENQALLIP LSLTLDEQQT 490 500 510 520 530 540 ASWQQSQTAL ADLGFDIQTK QWQGQTRLTI QKVPTCLREQ NLQQLLFSLF NQQAVDCAEF 550 560 570 580 FAKNATYPTA SSLSEAVALL AEVEVLPRGK AMLEALRVEV DFEEMLINL

References

[1]

"Complete genome sequence of Haemophilus parasuis SH0165." Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R., Jin M., Jin Q., Chen H. J. Bacteriol. 191:1359-1360(2009) [PubMed: 19074396] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SH0165 EMBL ACL32933.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001321 Genomic DNA. Translation: ACL32933.1.
RefSeq	YP_002475881.1. NC_011852.1.
3D structure databases
ProteinModelPortal	B8F6I1.
ModBase	Search...
Protein-protein interaction databases
STRING	B8F6I1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7277491.
GenomeReviews	Gene locus HAPS_1353 in contig CP001321_GR.
KEGG	hap:HAPS_1353.
PATRIC	20194985. VBIHaePar127548_1328.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG520262.
OMA	EVANLFF.
ProtClustDB	PRK00095.
Family and domain databases
HAMAP	MF_00149. DNA_mis_repair. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR002099. DNA_mismatch_repair. IPR013507. DNA_mismatch_repair_C. IPR014762. DNA_mismatch_repair_CS. IPR020667. DNA_mismatch_repair_MutL. IPR014763. DNA_mismatch_repair_N. IPR014790. MutL_C. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KO	K03572.
PANTHER	PTHR10073. DNA_mis_repair. 1 hit.
Pfam	PF01119. DNA_mis_repair. 1 hit. PF02518. HATPase_c. 1 hit. PF08676. MutL_C. 1 hit. [Graphical view]
SMART	SM00387. HATPase_c. 1 hit. SM00853. MutL_C. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR00585. Mutl. 1 hit.
PROSITE	PS00058. DNA_MISMATCH_REPAIR_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8F6I1_HAEPS

Accession

Primary (citable) accession number: B8F6I1

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)