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Protein

Superoxide dismutase [Cu-Zn]

Gene

sodC

Organism
Haemophilus parasuis serovar 5 (strain SH0165)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. superoxide dismutase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciHPAR557723:GH24-756-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodCImported
Ordered Locus Names:HAPS_0756Imported
OrganismiHaemophilus parasuis serovar 5 (strain SH0165)Imported
Taxonomic identifieri557723 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000006743: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi557723.HAPS_0756.

Structurei

3D structure databases

ProteinModelPortaliB8F4Z8.
SMRiB8F4Z8. Positions 27-179.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263449.
KOiK04565.
OMAiDADDYKT.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8F4Z8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKTVLTLAL TALFGFSTSA IANSATQIEV KVQQLDLQNG NKDVGTVTIT
60 70 80 90 100
ESPYGLVFTP NLKGLSHGLH GFHIHEKPSC EPKEKDGKLV AGLGAGGHWD
110 120 130 140 150
PKETKKHGYP WSDEAHLGDL PALAVDHEGN ATNPVLAPRL KKLEEVKGRS
160 170 180
LMIHAGGDNH SDHPAPLGGG GARMACGVIN
Length:180
Mass (Da):19,004
Last modified:March 3, 2009 - v1
Checksum:i9EAD6500EB43031F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001321 Genomic DNA. Translation: ACL32400.1.
RefSeqiYP_002475348.1. NC_011852.1.

Genome annotation databases

EnsemblBacteriaiACL32400; ACL32400; HAPS_0756.
GeneIDi7278271.
KEGGihap:HAPS_0756.
PATRICi20193781. VBIHaePar127548_0755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001321 Genomic DNA. Translation: ACL32400.1.
RefSeqiYP_002475348.1. NC_011852.1.

3D structure databases

ProteinModelPortaliB8F4Z8.
SMRiB8F4Z8. Positions 27-179.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi557723.HAPS_0756.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL32400; ACL32400; HAPS_0756.
GeneIDi7278271.
KEGGihap:HAPS_0756.
PATRICi20193781. VBIHaePar127548_0755.

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263449.
KOiK04565.
OMAiDADDYKT.
OrthoDBiEOG6K13RS.

Enzyme and pathway databases

BioCyciHPAR557723:GH24-756-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of Haemophilus parasuis SH0165."
    Yue M., Yang F., Yang J., Bei W., Cai X., Chen L., Dong J., Zhou R., Jin M., Jin Q., Chen H.
    J. Bacteriol. 191:1359-1360(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SH0165Imported.

Entry informationi

Entry nameiB8F4Z8_HAEPS
AccessioniPrimary (citable) accession number: B8F4Z8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 7, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.