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Protein

Superoxide dismutase [Cu-Zn]

Gene

sodC

Organism
Haemophilus parasuis serovar 5 (strain SH0165)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:sodCImported
Ordered Locus Names:HAPS_0756Imported
OrganismiHaemophilus parasuis serovar 5 (strain SH0165)Imported
Taxonomic identifieri557723 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000006743 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_500286875023 – 180Superoxide dismutase [Cu-Zn]Sequence analysisAdd BLAST158

Interactioni

Protein-protein interaction databases

STRINGi557723.HAPS_0756.

Structurei

3D structure databases

ProteinModelPortaliB8F4Z8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 179Sod_CuInterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108Z7T. Bacteria.
COG2032. LUCA.
HOGENOMiHOG000263449.
KOiK04565.
OMAiHKGDIGN.

Family and domain databases

CDDicd00305. Cu-Zn_Superoxide_Dismutase. 1 hit.
Gene3Di2.60.40.200. 1 hit.
InterProiView protein in InterPro
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
PfamiView protein in Pfam
PF00080. Sod_Cu. 1 hit.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiView protein in PROSITE
PS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B8F4Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKTVLTLAL TALFGFSTSA IANSATQIEV KVQQLDLQNG NKDVGTVTIT
60 70 80 90 100
ESPYGLVFTP NLKGLSHGLH GFHIHEKPSC EPKEKDGKLV AGLGAGGHWD
110 120 130 140 150
PKETKKHGYP WSDEAHLGDL PALAVDHEGN ATNPVLAPRL KKLEEVKGRS
160 170 180
LMIHAGGDNH SDHPAPLGGG GARMACGVIN
Length:180
Mass (Da):19,004
Last modified:March 3, 2009 - v1
Checksum:i9EAD6500EB43031F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001321 Genomic DNA. Translation: ACL32400.1.
RefSeqiWP_005710764.1. NC_011852.1.

Genome annotation databases

EnsemblBacteriaiACL32400; ACL32400; HAPS_0756.
GeneIDi7278271.
KEGGihap:HAPS_0756.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB8F4Z8_HAEPS
AccessioniPrimary (citable) accession number: B8F4Z8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 7, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported