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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Haemophilus parasuis serovar 5 (strain SH0165) (Glaesserella parasuis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei545UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciHPAR557723:G1GUF-358-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:HAPS_0357Imported
OrganismiHaemophilus parasuis serovar 5 (strain SH0165) (Glaesserella parasuis)Imported
Taxonomic identifieri557723 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeGlaesserella
Proteomesi
  • UP000006743 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi557723.HAPS_0357

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238648
KOiK01595
OMAiPWVFGWT

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B8F3Y8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQIYESMRS NIHMLGDFLG ETIRDAQGNE ILDLIENIRI LSRASRSGDE
60 70 80 90 100
KSREQLLDIL ANISNEDVIP VARAFSQFLN LTNIAEQYHT ISRHNKDAAL
110 120 130 140 150
GERSMGALFT RLKAQNVPAE KVIATVEKLL IDLVLTAHPT EVTRRSLVHK
160 170 180 190 200
HVEINRCLSR LEHDDLTDAE TTKLKRRLMQ LIALAWHTNE IRTQRPTPVD
210 220 230 240 250
EAKWGMAVIE NSLWKAVPEF CRQLNFHLEK NFGVQHPVGL APVRFSSWMG
260 270 280 290 300
GDRDGNPFVT AETTRKVLRM NRYKAAELFL EDIKSLADEL SVIHATDAFR
310 320 330 340 350
AKYGDHLEPY RVVVKDLRAK LIKTLAYYDE LLQDKPLTIS RDEILTDDEQ
360 370 380 390 400
LWEPLYDCYQ SLHQCGMRII ANGGLLDCLR RIRCFGLGLS RLDIRQESTR
410 420 430 440 450
HEMAIAEITR YIGLGDYSQW TEDDKQAFLV RELSSRRPLV PTNWTPSPET
460 470 480 490 500
KEILDTCKVV AEQPEGVISA YVISMAREAS DVLAVHLLLK EAGCKTTIPV
510 520 530 540 550
SPLFETLDDL DHCEKVMTDL FNIGWYRGVI NNKQMVMIGY SDSAKDAGML
560 570 580 590 600
AASWAQYRAQ EALVNLSEKY NVELTLFHGR GGTIGRGGAP AHAALLSQPP
610 620 630 640 650
RSLKNGLRVT EQGEMIRFKL GLPAVAVSSL DLYASAILEA NLCPPPEPKQ
660 670 680 690 700
EWRDIMDKGS EISCDIYRGI VRGEPDFVPY FRAATPEQEL SKLPLGSRPA
710 720 730 740 750
KRNPNGGVES LRAIPWIFAW MQNRLMLPAW LGAGQALQQL IEQGNEVLLK
760 770 780 790 800
EMCTEWPFFS TRIGMLEMVF SKADLWLAEH YDQRLVPQHL HRLGNTLRNQ
810 820 830 840 850
LAADINTVLS LAHEGQLMAD LPWVAESIAL RNVYTDPLNL LQVELLHRLR
860 870
AEGENPNPAL EQALMITITG IAAGMRNTG
Length:879
Mass (Da):99,183
Last modified:March 3, 2009 - v1
Checksum:iF9881B5E14A2C56E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001321 Genomic DNA Translation: ACL32040.1
RefSeqiWP_012621691.1, NC_011852.1

Genome annotation databases

EnsemblBacteriaiACL32040; ACL32040; HAPS_0357
GeneIDi7277339
KEGGihap:HAPS_0357
PATRICifig|557723.8.peg.363

Similar proteinsi

Entry informationi

Entry nameiB8F3Y8_HAEPS
AccessioniPrimary (citable) accession number: B8F3Y8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health