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B8ERC6 (SURE_METSB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
5'-nucleotidase surE
EC=3.1.3.5
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene names
Name:surE
Ordered Locus Names:Msil_1345
OrganismMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP]
Taxonomic identifier395965 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella

Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060

Cofactor

Binds 1 divalent metal cation per subunit By similarity.

Subcellular location

Cytoplasm Potential HAMAP MF_00060.

Sequence similarities

Belongs to the surE nucleotidase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function5'-nucleotidase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2522525'-nucleotidase surE HAMAP MF_00060
PRO_1000196610

Sites

Metal binding81Divalent metal cation By similarity
Metal binding91Divalent metal cation By similarity
Metal binding401Divalent metal cation By similarity
Metal binding931Divalent metal cation By similarity

Sequences

Sequence LengthMass (Da)Tools
B8ERC6 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: A0243D9867D17845

FASTA25226,872
        10         20         30         40         50         60 
MRILVTNDDG VHAPGLRVLE EIAAALSDDV YVVAPESDQS GVAHSLSLND PLRLRRISER 

        70         80         90        100        110        120 
RYAVKGTPTD CVIMGVRRIL DGREPDVVLS GVNSGQNVAE DVIYSGTVAG AMEGAILGIP 

       130        140        150        160        170        180 
AIALSQAYGR AGREKAFWSC AQAHAPGLIE KILATGVPAN TVVNVNFPDC PPDAVEGVAV 

       190        200        210        220        230        240 
TAQGRRGYLV NVDARSDGRG NPYYWIAFDR PFSEPGKGTD VEALAHNRIS VTPLRLDITD 

       250 
TPTLTRYAQA LL

« Hide

References

[1]"Complete sequence of Methylocella silvestris BL2."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. expand/collapse author list , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001280 Genomic DNA. Translation: ACK50310.1.
RefSeqYP_002361672.1. NC_011666.1.

3D structure databases

ProteinModelPortalB8ERC6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8ERC6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7091683.
GenomeReviewsGene locus Msil_1345 in contig CP001280_GR.
KEGGmsl:Msil_1345.
PATRIC22598187. VBIMetSil55537_1471.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG600532.
OMAHAPALIR.

Family and domain databases

HAMAPMF_00060. SurE.
[Tree]
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
Gene3DG3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KOK03787.
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMsTIGR00087. SurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSURE_METSB
AccessionPrimary (citable) accession number: B8ERC6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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