B8EQM2 (SECB_METSB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	Msil_0314

Organism

Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP]

Taxonomic identifier

395965 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella

Protein attributes

Sequence length	161 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity. HAMAP MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00821.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 161	161	Protein-export protein secB HAMAP MF_00821		PRO_1000148705

Sequences

	Sequence		Length	Mass (Da)
	B8EQM2 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 1BF80CEDCA572B9A	FASTA	161	17,593
	10 20 30 40 50 60 MANGNGTGAE VDAAPAINAM VQYTKDFSFE NPNAPRSLGP QDKPPNIQIQ VNVNAKQVAE 70 80 90 100 110 120 NDFEVNILLE GSAKTDADTL FKFELDYAGL FRLINIPQSD AHPVIMIECP RLLFPFARQI 130 140 150 160 IADAVRSGGF PPLYIDPIDF AALYRQRMSQ VAANEQAPTV A

References

[1]

"Complete sequence of Methylocella silvestris BL2." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001280 Genomic DNA. Translation: ACK49293.1.
RefSeq	YP_002360655.1. NC_011666.1.
3D structure databases
ProteinModelPortal	B8EQM2.
ModBase	Search...
Protein-protein interaction databases
STRING	B8EQM2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7091532.
GenomeReviews	Gene locus Msil_0314 in contig CP001280_GR.
KEGG	msl:Msil_0314.
PATRIC	22595899. VBIMetSil55537_0346.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG294212.
OMA	GFPPLMI.
ProtClustDB	PRK05751.
Family and domain databases
HAMAP	MF_00821. SecB. [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
KO	K03071.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
SUPFAM	SSF54611. SecB. 1 hit.
TIGRFAMs	TIGR00809. SecB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_METSB

Accession

Primary (citable) accession number: B8EQM2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program